Expression of AHSA1 in cancer - Summary - The Human Protein Atlas

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AHSA1

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TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	AHSA1
Gene description	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast)
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Supported based on 2 antibodies. HPA000903 , CAB006244
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable).
Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA000903	CAB006244

GENE INFORMATION
Gene name	AHSA1 (HGNC Symbol)
Synonyms	Aha1, C14orf3, p38
Description	AHA1, activator of heat shock 90kDa protein ATPase homolog 1 (yeast) (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q24.3
Chromosome location (bp)	77457870 - 77469474
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000100591 (version 83.38)
Entrez gene	10598
UniProt	O95433 (UniProt - Evidence at protein level)
neXtProt	NX_O95433
Antibodypedia	AHSA1 antibodies

PROTEIN BROWSER

AHSA1-001	AHSA1-002	AHSA1-004	AHSA1-006	AHSA1-011	AHSA1-012

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
AHSA1-001 ENSP00000216479 ENST00000216479	O95433 [Direct mapping] Activator of 90 kDa heat shock protein ATPase homolog 1 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0001671 [ATPase activator activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005829 [cytosol] GO:0006950 [response to stress] GO:0032781 [positive regulation of ATPase activity] GO:0051087 [chaperone binding] GO:0070062 [extracellular exosome] Show all	338 aa 38.3 kDa	No	0
AHSA1-002 ENSP00000440108 ENST00000535854	O95433 [Direct mapping] Activator of 90 kDa heat shock protein ATPase homolog 1 Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001671 [ATPase activator activity] GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005783 [endoplasmic reticulum] GO:0005829 [cytosol] GO:0006950 [response to stress] GO:0032781 [positive regulation of ATPase activity] GO:0051087 [chaperone binding] GO:0070062 [extracellular exosome] Show all	288 aa 32.3 kDa	No	0
AHSA1-004 ENSP00000451569 ENST00000555133	G3V438 [Direct mapping] Activator of 90 kDa heat shock protein ATPase homolog 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005737 [cytoplasm] GO:0006950 [response to stress] Show all	203 aa 23 kDa	No	0
AHSA1-006 ENSP00000451467 ENST00000555517	G3V3W9 [Direct mapping] Activator of 90 kDa heat shock protein ATPase homolog 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001671 [ATPase activator activity] GO:0032781 [positive regulation of ATPase activity] GO:0051087 [chaperone binding] Show all	100 aa 11.6 kDa	No	0
AHSA1-011 ENSP00000451475 ENST00000553374	H0YJG7 [Direct mapping] Activator of 90 kDa heat shock protein ATPase homolog 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001671 [ATPase activator activity] GO:0006950 [response to stress] GO:0032781 [positive regulation of ATPase activity] GO:0051087 [chaperone binding] Show all	216 aa 23.7 kDa	No	0
AHSA1-012 ENSP00000452127 ENST00000555729	H0YJU2 [Direct mapping] Activator of 90 kDa heat shock protein ATPase homolog 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0001671 [ATPase activator activity] GO:0006950 [response to stress] GO:0032781 [positive regulation of ATPase activity] GO:0051087 [chaperone binding] Show all	133 aa 14.9 kDa	No	0

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.