Expression of PCNX in cancer - Summary - The Human Protein Atlas

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PCNX

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	PCNX
Gene description	Pecanex homolog (Drosophila)
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	5
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	PCNX (HGNC Symbol)
Synonyms	KIAA0805, KIAA0995, PCNXL1, pecanex
Description	Pecanex homolog (Drosophila) (HGNC Symbol)
Entrez gene summary
Chromosome	14
Cytoband	q24.2
Chromosome location (bp)	70907405 - 71115382
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000100731 (version 83.38)
Entrez gene	22990
UniProt	Q96RV3 (UniProt - Evidence at protein level)
neXtProt	NX_Q96RV3
Antibodypedia	PCNX antibodies

PROTEIN BROWSER

PCNX-001	PCNX-003	PCNX-004	PCNX-008	PCNX-014

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
PCNX-001 ENSP00000304192 ENST00000304743	Q96RV3 [Direct mapping] Pecanex-like protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	2341 aa 258.7 kDa	No	>9
PCNX-003 ENSP00000451016 ENST00000554691	H0YJ91 [Direct mapping] Pecanex-like protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	1328 aa 148.9 kDa	No	>9
PCNX-004 ENSP00000396617 ENST00000439984	Q96RV3 [Direct mapping] Pecanex-like protein 1 Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based >9TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	2230 aa 247 kDa	No	>9
PCNX-008 ENSP00000450947 ENST00000555780	H0YJ76 [Direct mapping] Pecanex-like protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		95 aa 11.3 kDa	No	0
PCNX-014 ENSP00000452517 ENST00000556849	H0YJZ0 [Direct mapping] Pecanex-like protein 1 Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	199 aa 22.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.