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Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

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Score

Score

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Antibodies

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CCNB1IP1
  • TISSUE

  • CELL

  • PATHOLOGY

TISSUE ATLAS

GENE/PROTEIN

Dictionary


Tissue proteome

GENERAL INFORMATION

Gene name

CCNB1IP1

Gene description

Cyclin B1 interacting protein 1, E3 ubiquitin protein ligase

Protein class

Cancer-related genes
Predicted intracellular proteins
Predicted secreted proteins

Predicted localization

Intracellular,Secreted

Number of transcripts

9
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY

Reliability score

Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM) Protein expression (score)
Brain
N/A
Cerebral cortex
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Thyroid gland
N/A
Parathyroid gland
N/A
Adrenal gland
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Bone marrow
N/A
Lymph node
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Heart muscle
N/A
Skeletal muscle
N/A
Smooth muscle
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Gallbladder
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Salivary gland
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Small intestine
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Urinary bladder
N/A
Male tissues
N/A
Testis
N/A
Epididymis
N/A
Prostate
N/A
Seminal vesicle
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Cervix, uterine
N/A
Endometrium
N/A
Fallopian tube
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Adipose tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW

Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW

HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

CCNB1IP1 (HGNC Symbol)

Synonyms

C14orf18, HEI10

Description

Cyclin B1 interacting protein 1, E3 ubiquitin protein ligase (HGNC Symbol)

Entrez gene summary

HEI10 is a member of the E3 ubiquitin ligase family and functions in progression of the cell cycle through G(2)/M.[supplied by OMIM, Apr 2004]

Chromosome

14

Cytoband

q11.2

Chromosome location (bp)

20311368 - 20333312

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000100814 (version 83.38)

Entrez gene

57820

UniProt

Q9NPC3 (UniProt - Evidence at protein level)

neXtProt

NX_Q9NPC3

Antibodypedia

CCNB1IP1 antibodies

PROTEIN BROWSER

CCNB1IP1-001
CCNB1IP1-002
CCNB1IP1-004
CCNB1IP1-005
CCNB1IP1-007
CCNB1IP1-010
CCNB1IP1-011
CCNB1IP1-201
CCNB1IP1-202

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

CCNB1IP1-001
ENSP00000381235
ENST00000398169
Q9NPC3 [Direct mapping]
E3 ubiquitin-protein ligase CCNB1IP1
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Show all
GO:0000795 [synaptonemal complex]
GO:0005515 [protein binding]
GO:0007131 [reciprocal meiotic recombination]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0051026 [chiasma assembly]
GO:0061630 [ubiquitin protein ligase activity]
Show all
277 aa
31.5 kDa
No 0
CCNB1IP1-002
ENSP00000381226
ENST00000398160
Q9NPC3 [Direct mapping]
E3 ubiquitin-protein ligase CCNB1IP1
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Show all
GO:0000795 [synaptonemal complex]
GO:0005515 [protein binding]
GO:0007131 [reciprocal meiotic recombination]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0051026 [chiasma assembly]
GO:0061630 [ubiquitin protein ligase activity]
Show all
277 aa
31.5 kDa
No 0
CCNB1IP1-004
ENSP00000381229
ENST00000398163
Q9NPC3 [Direct mapping]
E3 ubiquitin-protein ligase CCNB1IP1
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Show all
GO:0000795 [synaptonemal complex]
GO:0005515 [protein binding]
GO:0007131 [reciprocal meiotic recombination]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0051026 [chiasma assembly]
GO:0061630 [ubiquitin protein ligase activity]
Show all
277 aa
31.5 kDa
No 0
CCNB1IP1-005
ENSP00000351810
ENST00000358932
Q9NPC3 [Direct mapping]
E3 ubiquitin-protein ligase CCNB1IP1
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Protein evidence (Kim et al 2014)
Show all
GO:0000795 [synaptonemal complex]
GO:0005515 [protein binding]
GO:0007131 [reciprocal meiotic recombination]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0051026 [chiasma assembly]
GO:0061630 [ubiquitin protein ligase activity]
Show all
277 aa
31.5 kDa
No 0
CCNB1IP1-007
ENSP00000452486
ENST00000557665
G3V5S3 [Direct mapping]
E3 ubiquitin-protein ligase CCNB1IP1
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Show all
GO:0005515 [protein binding]
GO:0007131 [reciprocal meiotic recombination]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0061630 [ubiquitin protein ligase activity]
Show all
154 aa
17.6 kDa
No 0
CCNB1IP1-010
ENSP00000452312
ENST00000556563
G3V5E6 [Direct mapping]
E3 ubiquitin-protein ligase CCNB1IP1
Show all
Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Show all
GO:0007131 [reciprocal meiotic recombination]
GO:0016567 [protein ubiquitination]
GO:0061630 [ubiquitin protein ligase activity]
Show all
68 aa
8 kDa
Yes 0
CCNB1IP1-011
ENSP00000452182
ENST00000553291
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Show all
4 aa
0.5 kDa
No 0
CCNB1IP1-201
ENSP00000337396
ENST00000353689
Q9NPC3 [Direct mapping]
E3 ubiquitin-protein ligase CCNB1IP1
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Protein evidence (Kim et al 2014)
Show all
GO:0000795 [synaptonemal complex]
GO:0005515 [protein binding]
GO:0007131 [reciprocal meiotic recombination]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0051026 [chiasma assembly]
GO:0061630 [ubiquitin protein ligase activity]
Show all
277 aa
31.5 kDa
No 0
CCNB1IP1-202
ENSP00000409896
ENST00000437553
Q9NPC3 [Direct mapping]
E3 ubiquitin-protein ligase CCNB1IP1
Show all
Predicted intracellular proteins
Cancer-related genes
   COSMIC somatic mutations in cancer genes
   COSMIC Somatic Mutations
   COSMIC Translocations
Protein evidence (Kim et al 2014)
Show all
GO:0000794 [condensed nuclear chromosome]
GO:0000795 [synaptonemal complex]
GO:0001825 [blastocyst formation]
GO:0005515 [protein binding]
GO:0007131 [reciprocal meiotic recombination]
GO:0007286 [spermatid development]
GO:0008270 [zinc ion binding]
GO:0016567 [protein ubiquitination]
GO:0016874 [ligase activity]
GO:0051026 [chiasma assembly]
GO:0061630 [ubiquitin protein ligase activity]
Show all
277 aa
31.5 kDa
No 0

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The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.