Tissue expression of TRIP11 - Summary - The Human Protein Atlas

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TRIP11

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TISSUE

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CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	TRIP11
Gene description	Thyroid hormone receptor interactor 11
Protein class	Cancer-related genes Disease related genes Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression with a granular pattern.

DATA RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Supported based on 1 antibody. HPA002570
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	TRIP11 (HGNC Symbol)
Synonyms	CEV14, GMAP-210, GMAP210, Trip230
Description	Thyroid hormone receptor interactor 11 (HGNC Symbol)
Entrez gene summary	This gene was identified based on the interaction of its protein product with thyroid hormone receptor beta. This protein is associated with the Golgi apparatus. The N-terminal region of the protein binds Golgi membranes and the C-terminal region binds the minus ends of microtubules; thus, the protein is thought to play a role in assembly and maintenance of the Golgi ribbon structure around the centrosome. Mutations in this gene cause achondrogenesis type IA.[provided by RefSeq, Mar 2010]
Chromosome	14
Cytoband	q32.12
Chromosome location (bp)	91965991 - 92040896
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000100815 (version 83.38)
Entrez gene	9321
UniProt	Q15643 (UniProt - Evidence at protein level)
neXtProt	NX_Q15643
Antibodypedia	TRIP11 antibodies

PROTEIN BROWSER

TRIP11-001	TRIP11-002	TRIP11-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TRIP11-001 ENSP00000267622 ENST00000267622	Q15643 [Direct mapping] Thyroid receptor-interacting protein 11 Show all	Phobius predicted secreted proteins Predicted intracellular proteins Plasma proteins Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000042 [protein targeting to Golgi] GO:0000139 [Golgi membrane] GO:0002079 [inner acrosomal membrane] GO:0002080 [acrosomal membrane] GO:0002081 [outer acrosomal membrane] GO:0003281 [ventricular septum development] GO:0003713 [transcription coactivator activity] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005794 [Golgi apparatus] GO:0005801 [cis-Golgi network] GO:0005856 [cytoskeleton] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006996 [organelle organization] GO:1903506 [regulation of nucleic acid-templated transcription] Show all	1979 aa 227.6 kDa	No	0
TRIP11-002 ENSP00000451032 ENST00000554357	H0YJ97 [Direct mapping] Thyroid receptor-interacting protein 11 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Protein evidence (Ezkurdia et al 2014) Show all	GO:0000042 [protein targeting to Golgi] GO:0005515 [protein binding] GO:0005622 [intracellular] Show all	1695 aa 195.7 kDa	No	0
TRIP11-005 ENSP00000451944 ENST00000555516	G3V4R7 [Direct mapping] Thyroid receptor-interacting protein 11 Show all	Predicted intracellular proteins Cancer-related genes Mutational cancer driver genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Protein evidence (Ezkurdia et al 2014) Show all		67 aa 7.7 kDa	No	0

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.