Expression of COL20A1 in cancer - Summary - The Human Protein Atlas

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COL20A1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	COL20A1
Gene description	Collagen, type XX, alpha 1
Protein class	Predicted intracellular proteins Predicted secreted proteins
Predicted localization	Intracellular,Secreted
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enriched (glioma)
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (cerebral cortex)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
Reliability score	Uncertain based on 1 antibody. HPA051962
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enriched (glioma)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA051962

GENE INFORMATION
Gene name	COL20A1 (HGNC Symbol)
Synonyms	KIAA1510
Description	Collagen, type XX, alpha 1 (HGNC Symbol)
Entrez gene summary
Chromosome	20
Cytoband	q13.33
Chromosome location (bp)	63293186 - 63334851
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000101203 (version 83.38)
Entrez gene	57642
UniProt	Q9P218 (UniProt - Evidence at protein level)
neXtProt	NX_Q9P218
Antibodypedia	COL20A1 antibodies

PROTEIN BROWSER

COL20A1-001	COL20A1-004	COL20A1-006	COL20A1-009

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
COL20A1-001 ENSP00000414753 ENST00000422202	Q9P218 [Direct mapping] Collagen alpha-1(XX) chain Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0005581 [collagen trimer] GO:0005615 [extracellular space] GO:0005788 [endoplasmic reticulum lumen] GO:0030198 [extracellular matrix organization] GO:0031012 [extracellular matrix] Show all	1297 aa 137.3 kDa	Yes	0
COL20A1-004 ENSP00000410799 ENST00000415763	B7ZBI4 [Direct mapping] Collagen alpha-1(XX) chain Show all	Predicted intracellular proteins Show all		401 aa 41.9 kDa	No	0
COL20A1-006 ENSP00000351767 ENST00000358894	Q9P218 [Direct mapping] Collagen alpha-1(XX) chain Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Show all	GO:0005515 [protein binding] GO:0005576 [extracellular region] GO:0005581 [collagen trimer] GO:0005615 [extracellular space] GO:0005788 [endoplasmic reticulum lumen] GO:0030198 [extracellular matrix organization] GO:0031012 [extracellular matrix] Show all	1284 aa 135.8 kDa	Yes	0
COL20A1-009 ENSP00000406345 ENST00000455906	B7ZBI5 [Direct mapping] Collagen alpha-1(XX) chain Show all	Predicted intracellular proteins Show all		250 aa 25.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.