Expression of APMAP in cancer - Summary - The Human Protein Atlas

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APMAP

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	APMAP
Gene description	Adipocyte plasma membrane associated protein
Protein class	Plasma proteins Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Ubiquitous cytoplasmic, sometimes nuclear expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Uncertain based on 1 antibody. HPA012863
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA012863

GENE INFORMATION
Gene name	APMAP (HGNC Symbol)
Synonyms	BSCv, C20orf3
Description	Adipocyte plasma membrane associated protein (HGNC Symbol)
Entrez gene summary
Chromosome	20
Cytoband	p11.21
Chromosome location (bp)	24962925 - 24992979
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000101474 (version 83.38)
Entrez gene	57136
UniProt	Q9HDC9 (UniProt - Evidence at protein level)
neXtProt	NX_Q9HDC9
Antibodypedia	APMAP antibodies

PROTEIN BROWSER

APMAP-001	APMAP-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
APMAP-001 ENSP00000217456 ENST00000217456	Q9HDC9 [Direct mapping] Adipocyte plasma membrane-associated protein Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004064 [arylesterase activity] GO:0005783 [endoplasmic reticulum] GO:0008150 [biological_process] GO:0009058 [biosynthetic process] GO:0009986 [cell surface] GO:0016020 [membrane] GO:0016021 [integral component of membrane] GO:0016844 [strictosidine synthase activity] GO:0070062 [extracellular exosome] Show all	416 aa 46.5 kDa	No	1
APMAP-002 ENSP00000395874 ENST00000451442	H0Y512 [Direct mapping] Adipocyte plasma membrane-associated protein Show all	MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0009058 [biosynthetic process] GO:0016021 [integral component of membrane] GO:0016844 [strictosidine synthase activity] Show all	409 aa 45.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.