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A majority of cancer cells displayed weak to moderate cytoplasmic immunoreactivity. Most lymphomas, ovarian and cervical cancers were negative.
GENE INFORMATION
Gene name
STS (HGNC Symbol)
Synonyms
ARSC, ARSC1
Description
Steroid sulfatase (microsomal), isozyme S (HGNC Symbol)
Entrez gene summary
The protein encoded by this gene catalyzes the conversion of sulfated steroid precursors to estrogens during pregnancy. The encoded protein is found in the endoplasmic reticulum, where it acts as a homodimer. Mutations in this gene are known to cause X-linked ichthyosis (XLI). [provided by RefSeq, Jul 2008]