We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.
Breast and prostate cancers as well as several pancreatic cancers displayed moderate to strong cytoplasmic staining often combined with membranous positivity. Colorectal, urothelial and female genital cancers showed moderate cytoplasmic staining. Remaining cancer tissues were in general weakly stained or negative.
Several breast and prostate cancers displayed moderate to strong cytoplasmic staining with membranous positivity in fractions of cases while most hepatocellular carcinomas, colorectal and thyroid cancers exhibited moderate positivity. Remaining cancer tissues were in general weakly stained or negative.
GENE INFORMATION
Gene name
SYTL4
Synonyms
Description
Synaptotagmin-like 4 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the synaptotagmin like protein family. Members of this family are characterized by an N-terminal Rab27 binding domain and C-terminal tandem C2 domains. The encoded protein binds specific small Rab GTPases and is involved in intracellular membrane trafficking. This protein binds Rab27 and may be involved in inhibiting dense core vesicle exocytosis. Alternate splicing results in multiple transcript variants that encode the same protein. [provided by RefSeq, Mar 2010]