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CENPI

GENERAL INFORMATION

Gene name

 CENPI

Gene description

 Centromere protein I

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 5
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Mixed
HPA (cell line):Expressed in all
HPA (normal tissue):Mixed

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Mixed

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 CENPI (HGNC Symbol)

Synonyms

 CENP-I, FSHPRH1, LRPR1, Mis6

Description

 Centromere protein I (HGNC Symbol)

Entrez gene summary

 The product of this gene is involved in the response of gonadal tissues to follicle-stimulating hormone. This gene is also a potential candidate for human X-linked disorders of gonadal development and gametogenesis. [provided by RefSeq, Jul 2008]

Chromosome

 X

Cytoband

 q22.1

Chromosome location (bp)

 101098218 - 101163681

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000102384 (version 83.38)

Entrez gene

 2491

UniProt

 Q92674 (UniProt - Evidence at protein level)

neXtProt

 NX_Q92674

Antibodypedia

 CENPI antibodies

PROTEIN BROWSER
CENPI-001
CENPI-002
CENPI-003
CENPI-004
CENPI-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CENPI-001
ENSP00000362017
ENST00000372926
Q92674 [Direct mapping]
Centromere protein I
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0000278 [mitotic cell cycle]
GO:0000776 [kinetochore]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006334 [nucleosome assembly]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007548 [sex differentiation]
GO:0034080 [CENP-A containing nucleosome assembly]
GO:0034508 [centromere complex assembly]
Show all
 522 aa
59.8 kDa 		No 0
CENPI-002
ENSP00000384546
ENST00000403304
Q5JX01 [Direct mapping]
Centromere protein I
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000776 [kinetochore]
GO:0034508 [centromere complex assembly]
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 75 aa
8.4 kDa 		No 0
CENPI-003
ENSP00000409173
ENST00000435570
Q5JX02 [Direct mapping]
Centromere protein I
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000776 [kinetochore]
GO:0034508 [centromere complex assembly]
Show all
 45 aa
5 kDa 		No 0
CENPI-004
ENSP00000362018
ENST00000372927
Q92674 [Direct mapping]
Centromere protein I
A0A024RCG4 [Target identity:100%; Query identity:100%]
FSH primary response (LRPR1 homolog, rat) 1, isoform CRA_b
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   MEMSAT3 predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000278 [mitotic cell cycle]
GO:0000776 [kinetochore]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006334 [nucleosome assembly]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007548 [sex differentiation]
GO:0034080 [CENP-A containing nucleosome assembly]
GO:0034508 [centromere complex assembly]
GO:0042699 [follicle-stimulating hormone signaling pathway]
Show all
 756 aa
86.7 kDa 		No 0
CENPI-201
ENSP00000399274
ENST00000423383
Q92674 [Direct mapping]
Centromere protein I
A0A024RCG4 [Target identity:100%; Query identity:100%]
FSH primary response (LRPR1 homolog, rat) 1, isoform CRA_b
Show all
   MEMSAT3 predicted membrane proteins
   THUMBUP predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000278 [mitotic cell cycle]
GO:0000776 [kinetochore]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0006334 [nucleosome assembly]
GO:0007264 [small GTPase mediated signal transduction]
GO:0007548 [sex differentiation]
GO:0034080 [CENP-A containing nucleosome assembly]
GO:0034508 [centromere complex assembly]
Show all
 756 aa
86.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.