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TAF7L

GENERAL INFORMATION

Gene name

 TAF7L

Gene description

 TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (testis)
GTEx:Tissue enriched (testis)
FANTOM5:Tissue enriched (testis)

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in seminiferous ducts in testis.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Approved based on 1 antibody.
HPA001879
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)

GENE INFORMATION

Gene name

 TAF7L (HGNC Symbol)

Synonyms

 CT40, TAF2Q

Description

 TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa (HGNC Symbol)

Entrez gene summary

 This gene is similar to a mouse gene that encodes a TATA box binding protein-associated factor, and shows testis-specific expression. The encoded protein could be a spermatogenesis-specific component of the DNA-binding general transcription factor complex TFIID. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2009]

Chromosome

 X

Cytoband

 q22.1

Chromosome location (bp)

 101268253 - 101293057

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000102387 (version 83.38)

Entrez gene

 54457

UniProt

 Q5H9L4 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q5H9L4

Antibodypedia

 TAF7L antibodies

PROTEIN BROWSER
TAF7L-001
TAF7L-002
TAF7L-003

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TAF7L-001
ENSP00000320283
ENST00000324762
Q5H9L4 [Direct mapping]
Transcription initiation factor TFIID subunit 7-like
A0A024RCI3 [Target identity:100%; Query identity:100%]
TAF7-like RNA polymerase II, TATA box binding protein (TBP)-associated factor, 50kDa, isoform CRA_a
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Predicted intracellular proteins
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GO:0003674 [molecular_function]
GO:0003713 [transcription coactivator activity]
GO:0005669 [transcription factor TFIID complex]
GO:0005737 [cytoplasm]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008134 [transcription factor binding]
GO:0008150 [biological_process]
GO:0030154 [cell differentiation]
GO:0035035 [histone acetyltransferase binding]
GO:0044212 [transcription regulatory region DNA binding]
GO:0051123 [RNA polymerase II transcriptional preinitiation complex assembly]
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 302 aa
34.7 kDa 		No 0
TAF7L-002
ENSP00000349235
ENST00000356784
Q5H9L4 [Direct mapping]
Transcription initiation factor TFIID subunit 7-like
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0003713 [transcription coactivator activity]
GO:0005669 [transcription factor TFIID complex]
GO:0005737 [cytoplasm]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008134 [transcription factor binding]
GO:0008150 [biological_process]
GO:0030154 [cell differentiation]
GO:0035035 [histone acetyltransferase binding]
GO:0044212 [transcription regulatory region DNA binding]
GO:0051123 [RNA polymerase II transcriptional preinitiation complex assembly]
Show all
 376 aa
43.6 kDa 		No 0
TAF7L-003
ENSP00000361998
ENST00000372907
Q5H9L4 [Direct mapping]
Transcription initiation factor TFIID subunit 7-like
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Show all
GO:0003674 [molecular_function]
GO:0003713 [transcription coactivator activity]
GO:0005669 [transcription factor TFIID complex]
GO:0005737 [cytoplasm]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0006367 [transcription initiation from RNA polymerase II promoter]
GO:0007275 [multicellular organismal development]
GO:0007283 [spermatogenesis]
GO:0008134 [transcription factor binding]
GO:0008150 [biological_process]
GO:0030154 [cell differentiation]
GO:0035035 [histone acetyltransferase binding]
GO:0044212 [transcription regulatory region DNA binding]
GO:0051123 [RNA polymerase II transcriptional preinitiation complex assembly]
Show all
 462 aa
52.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.