Fields »
ABOUT
HELP
BLOG
FGF14

Please wait until image is loaded before changing channels

GENERAL INFORMATION

Gene name

 FGF14

Gene description

 Fibroblast growth factor 14

Protein class

 Disease related genes
Predicted intracellular proteins
RAS pathway related proteins

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

Summary

 Localized to the nucleoli (fibrillar center).

RNA cell category

 Cell line enhanced (SH-SY5Y, SCLC-21H, U-87 MG)

Protein evidence

 Evidence at protein level

Main location

 Localized to the Nucleoli fibrillar center (approved)

DATA RELIABILITY

Reliability score

 Approved based on 1 antibody.
HPA049828
SHOW MORE

ASSAYS
RNA expression
Human cells

RNA EXPRESSION OVERVIEW
RNA cell line category: Cell line enhanced (SH-SY5Y, SCLC-21H, U-87 MG)
Organ
Origin
Category
Expression
Alphabetical
Cell lines sorted after organ of phenotypic resemblance.

HUMAN CELLS

Summary

 Localized to the nucleoli (fibrillar center).

Main location

 Nucleoli fibrillar center (approved)

 

 

 
Toggle channels
Low
High
G1
S
G2
M
N/A

Thumbnail

Antibody

Cell line

Location

Single-cell variation

Cell cycle dependent variation
HPA049828 HaCaT Nucleoli fibrillar center
HPA049828 SH-SY5Y Nucleoli fibrillar center
HPA049828 U-2 OS Nucleoli fibrillar center

GENE INFORMATION

Gene name

 FGF14 (HGNC Symbol)

Synonyms

 FHF4, SCA27

Description

 Fibroblast growth factor 14 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a member of the fibroblast growth factor (FGF) family. FGF family members possess broad mitogenic and cell survival activities, and are involved in a variety of biological processes, including embryonic development, cell growth, morphogenesis, tissue repair, tumor growth and invasion. A mutation in this gene is associated with autosomal dominant cerebral ataxia. Alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 13

Cytoband

 q33.1

Chromosome location (bp)

 101710804 - 102402457

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000102466 (version 83.38)

Entrez gene

 2259

UniProt

 Q92915 (UniProt - Evidence at protein level)

neXtProt

 NX_Q92915

Antibodypedia

 FGF14 antibodies

PROTEIN BROWSER
FGF14-001
FGF14-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
FGF14-001
ENSP00000365313
ENST00000376143
Q92915 [Direct mapping]
Fibroblast growth factor 14
Show all
Predicted intracellular proteins
RAS pathway related proteins
Disease related genes
Show all
GO:0002230 [positive regulation of defense response to virus by host]
GO:0005576 [extracellular region]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0007165 [signal transduction]
GO:0007254 [JNK cascade]
GO:0007267 [cell-cell signaling]
GO:0007399 [nervous system development]
GO:0008083 [growth factor activity]
GO:0008201 [heparin binding]
Show all
 247 aa
27.7 kDa 		No 0
FGF14-002
ENSP00000365301
ENST00000376131
Q92915 [Direct mapping]
Fibroblast growth factor 14
Show all
Predicted intracellular proteins
RAS pathway related proteins
Disease related genes
Show all
GO:0002230 [positive regulation of defense response to virus by host]
GO:0005576 [extracellular region]
GO:0005622 [intracellular]
GO:0005634 [nucleus]
GO:0005829 [cytosol]
GO:0007165 [signal transduction]
GO:0007254 [JNK cascade]
GO:0007267 [cell-cell signaling]
GO:0007268 [synaptic transmission]
GO:0007399 [nervous system development]
GO:0008083 [growth factor activity]
GO:0008201 [heparin binding]
GO:0008344 [adult locomotory behavior]
GO:0010765 [positive regulation of sodium ion transport]
GO:0048167 [regulation of synaptic plasticity]
GO:0050905 [neuromuscular process]
GO:0060078 [regulation of postsynaptic membrane potential]
GO:1901843 [positive regulation of high voltage-gated calcium channel activity]
GO:1903421 [regulation of synaptic vesicle recycling]
Show all
 252 aa
28.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.