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SUPT20H

GENERAL INFORMATION

Gene name

 SUPT20H

Gene description

 SPT20 homolog, SAGA complex component

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 8
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Pending external verification.

Reliability score

 Uncertain based on 2 antibodies.
HPA038906 , HPA038907
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Pancreatic cancer

STAINING SUMMARY
HPA038906
HPA038907

GENE INFORMATION

Gene name

 SUPT20H (HGNC Symbol)

Synonyms

 bA421P11.4, C13orf19, FAM48A, P38IP, SPT20

Description

 SPT20 homolog, SAGA complex component (HGNC Symbol)

Entrez gene summary

Chromosome

 13

Cytoband

 q13.3

Chromosome location (bp)

 37009312 - 37059713

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000102710 (version 83.38)

Entrez gene

 55578

UniProt

 Q8NEM7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q8NEM7

Antibodypedia

 SUPT20H antibodies

PROTEIN BROWSER
SUPT20H-001
SUPT20H-007
SUPT20H-008
SUPT20H-009
SUPT20H-016
SUPT20H-017
SUPT20H-021
SUPT20H-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
SUPT20H-001
ENSP00000353388
ENST00000360252
Q8NEM7 [Direct mapping]
Transcription factor SPT20 homolog
A0A024RDW2 [Target identity:100%; Query identity:100%]
Family with sequence similarity 48, member A, isoform CRA_c
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124 [SAGA complex]
GO:0003712 [transcription cofactor activity]
GO:0005515 [protein binding]
GO:0005730 [nucleolus]
GO:0006325 [chromatin organization]
GO:0006914 [autophagy]
GO:0007369 [gastrulation]
GO:0070461 [SAGA-type complex]
Show all
 733 aa
80.1 kDa 		No 0
SUPT20H-007
ENSP00000348512
ENST00000356185
Q8NEM7 [Direct mapping]
Transcription factor SPT20 homolog
A0A024RDW2 [Target identity:100%; Query identity:100%]
Family with sequence similarity 48, member A, isoform CRA_c
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124 [SAGA complex]
GO:0003712 [transcription cofactor activity]
GO:0005515 [protein binding]
GO:0005730 [nucleolus]
GO:0006325 [chromatin organization]
GO:0006914 [autophagy]
GO:0007369 [gastrulation]
GO:0070461 [SAGA-type complex]
Show all
 733 aa
80.1 kDa 		No 0
SUPT20H-008
ENSP00000420170
ENST00000497318
C9JQS2 [Direct mapping]
Transcription factor SPT20 homolog
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124 [SAGA complex]
GO:0003712 [transcription cofactor activity]
GO:0005730 [nucleolus]
GO:1903506 [regulation of nucleic acid-templated transcription]
Show all
 190 aa
22.1 kDa 		No 0
SUPT20H-009
ENSP00000419787
ENST00000469488
H7C5F9 [Direct mapping]
Transcription factor SPT20 homolog
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124 [SAGA complex]
GO:0003712 [transcription cofactor activity]
GO:1903506 [regulation of nucleic acid-templated transcription]
Show all
 378 aa
39.7 kDa 		No 0
SUPT20H-016
ENSP00000218894
ENST00000350612
Q8NEM7 [Direct mapping]
Transcription factor SPT20 homolog
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124 [SAGA complex]
GO:0003712 [transcription cofactor activity]
GO:0005515 [protein binding]
GO:0005730 [nucleolus]
GO:0006325 [chromatin organization]
GO:0006914 [autophagy]
GO:0007369 [gastrulation]
GO:0070461 [SAGA-type complex]
Show all
 779 aa
85.8 kDa 		No 0
SUPT20H-017
ENSP00000419754
ENST00000464744
Q8NEM7 [Direct mapping]
Transcription factor SPT20 homolog
A0A024RDW2 [Target identity:100%; Query identity:100%]
Family with sequence similarity 48, member A, isoform CRA_c
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124 [SAGA complex]
GO:0003712 [transcription cofactor activity]
GO:0005515 [protein binding]
GO:0005730 [nucleolus]
GO:0006325 [chromatin organization]
GO:0006914 [autophagy]
GO:0007369 [gastrulation]
GO:0070461 [SAGA-type complex]
Show all
 733 aa
80.1 kDa 		No 0
SUPT20H-021
ENSP00000417510
ENST00000475892
Q8NEM7 [Direct mapping]
Transcription factor SPT20 homolog
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124 [SAGA complex]
GO:0003712 [transcription cofactor activity]
GO:0005515 [protein binding]
GO:0005730 [nucleolus]
GO:0006325 [chromatin organization]
GO:0006914 [autophagy]
GO:0007369 [gastrulation]
GO:0035948 [positive regulation of gluconeogenesis by positive regulation of transcription from RNA polymerase II promoter]
GO:0070461 [SAGA-type complex]
Show all
 811 aa
88 kDa 		No 0
SUPT20H-201
ENSP00000439000
ENST00000542180
F6S7C4 [Direct mapping]
Transcription factor SPT20 homolog
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000124 [SAGA complex]
GO:0003712 [transcription cofactor activity]
GO:1903506 [regulation of nucleic acid-templated transcription]
Show all
 736 aa
80.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.