Tissue expression of GSPT1 - Summary - The Human Protein Atlas

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GSPT1

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	GSPT1
Gene description	G1 to S phase transition 1
Protein class	Plasma proteins Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

Protein expression

Ubiquitous cytoplasmic expression.

DATA RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA052488
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	GSPT1 (HGNC Symbol)
Synonyms	eRF3a, ETF3A, GST1
Description	G1 to S phase transition 1 (HGNC Symbol)
Entrez gene summary
Chromosome	16
Cytoband	p13.13
Chromosome location (bp)	11868128 - 11916082
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000103342 (version 83.38)
Entrez gene	2935
UniProt	P15170 (UniProt - Evidence at protein level)
neXtProt	NX_P15170
Antibodypedia	GSPT1 antibodies

PROTEIN BROWSER

GSPT1-001	GSPT1-002	GSPT1-003	GSPT1-004	GSPT1-005	GSPT1-006	GSPT1-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GSPT1-001 ENSP00000398131 ENST00000434724	P15170 [Direct mapping] Eukaryotic peptide chain release factor GTP-binding subunit ERF3A Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000082 [G1/S transition of mitotic cell cycle] GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] GO:0002184 [cytoplasmic translational termination] GO:0003747 [translation release factor activity] GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005829 [cytosol] GO:0006479 [protein methylation] GO:0018444 [translation release factor complex] GO:0044822 [poly(A) RNA binding] Show all	637 aa 68.7 kDa	No	0
GSPT1-002 ENSP00000408399 ENST00000439887	P15170 [Direct mapping] Eukaryotic peptide chain release factor GTP-binding subunit ERF3A Show all	SPOCTOPUS predicted secreted proteins Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000082 [G1/S transition of mitotic cell cycle] GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] GO:0002184 [cytoplasmic translational termination] GO:0003747 [translation release factor activity] GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005829 [cytosol] GO:0006479 [protein methylation] GO:0018444 [translation release factor complex] GO:0044822 [poly(A) RNA binding] Show all	636 aa 68.6 kDa	No	0
GSPT1-003 ENSP00000399539 ENST00000420576	P15170 [Direct mapping] Eukaryotic peptide chain release factor GTP-binding subunit ERF3A Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000082 [G1/S transition of mitotic cell cycle] GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] GO:0002184 [cytoplasmic translational termination] GO:0003747 [translation release factor activity] GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005829 [cytosol] GO:0006479 [protein methylation] GO:0018444 [translation release factor complex] GO:0044822 [poly(A) RNA binding] Show all	499 aa 55.8 kDa	No	0
GSPT1-004 ENSP00000456057 ENST00000565267	H3BR35 [Direct mapping] Eukaryotic peptide chain release factor GTP-binding subunit ERF3A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0008152 [metabolic process] Show all	475 aa 52.8 kDa	No	0
GSPT1-005 ENSP00000454351 ENST00000563468	P15170 [Direct mapping] Eukaryotic peptide chain release factor GTP-binding subunit ERF3A Show all	Predicted intracellular proteins Plasma proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000082 [G1/S transition of mitotic cell cycle] GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay] GO:0002184 [cytoplasmic translational termination] GO:0003747 [translation release factor activity] GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0005622 [intracellular] GO:0005829 [cytosol] GO:0006479 [protein methylation] GO:0018444 [translation release factor complex] GO:0044822 [poly(A) RNA binding] Show all	499 aa 55.8 kDa	No	0
GSPT1-006 ENSP00000456897 ENST00000568849	H3BSV8 [Direct mapping] Eukaryotic peptide chain release factor GTP-binding subunit ERF3A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005525 [GTP binding] GO:0008152 [metabolic process] Show all	199 aa 22.2 kDa	No	0
GSPT1-007 ENSP00000454538 ENST00000562169	H3BMT9 [Direct mapping] Eukaryotic peptide chain release factor GTP-binding subunit ERF3A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		94 aa 10.2 kDa	No	0

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The Human Protein Atlas

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