Expression of CLUAP1 in cancer - Summary - The Human Protein Atlas

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CLUAP1

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CLUAP1
Gene description	Clusterin associated protein 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA036976
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PROGNOSTIC SUMMARY
Prognostic marker in endometrial cancer (favourable).
Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA036976

GENE INFORMATION
Gene name	CLUAP1 (HGNC Symbol)
Synonyms	CFAP22, FAP22, FLJ13297, IFT38, KIAA0643
Description	Clusterin associated protein 1 (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene contains a single coiled-coil region. Alternative splicing results in multiple transcript variants and protein isoforms. [provided by RefSeq, Jul 2012]
Chromosome	16
Cytoband	p13.3
Chromosome location (bp)	3500924 - 3539048
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000103351 (version 83.38)
Entrez gene	23059
UniProt	Q96AJ1 (UniProt - Evidence at protein level)
neXtProt	NX_Q96AJ1
Antibodypedia	CLUAP1 antibodies

PROTEIN BROWSER

CLUAP1-001	CLUAP1-002	CLUAP1-003	CLUAP1-004	CLUAP1-007	CLUAP1-009	CLUAP1-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CLUAP1-001 ENSP00000460850 ENST00000576634	Q96AJ1 [Direct mapping] Clusterin-associated protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005813 [centrosome] GO:0005929 [cilium] GO:0006996 [organelle organization] GO:0030992 [intraciliary transport particle B] GO:0042384 [cilium assembly] GO:0043231 [intracellular membrane-bounded organelle] GO:0072372 [primary cilium] GO:0097542 [ciliary tip] Show all	413 aa 48.1 kDa	No	0
CLUAP1-002 ENSP00000344392 ENST00000341633	J3KNW5 [Direct mapping] Clusterin-associated protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0005813 [centrosome] GO:0005929 [cilium] GO:0030992 [intraciliary transport particle B] GO:0042384 [cilium assembly] GO:0043231 [intracellular membrane-bounded organelle] Show all	432 aa 50.1 kDa	No	0
CLUAP1-003 ENSP00000460706 ENST00000571025	I3L3S9 [Direct mapping] Clusterin associated protein 1, isoform CRA_a; Clusterin-associated protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0005813 [centrosome] GO:0005929 [cilium] GO:0030992 [intraciliary transport particle B] GO:0042384 [cilium assembly] GO:0043231 [intracellular membrane-bounded organelle] Show all	387 aa 44.6 kDa	No	0
CLUAP1-004 ENSP00000460889 ENST00000572600	Q96AJ1 [Direct mapping] Clusterin-associated protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005813 [centrosome] GO:0005929 [cilium] GO:0006996 [organelle organization] GO:0030992 [intraciliary transport particle B] GO:0042384 [cilium assembly] GO:0043231 [intracellular membrane-bounded organelle] GO:0072372 [primary cilium] GO:0097542 [ciliary tip] Show all	247 aa 29.1 kDa	No	0
CLUAP1-007 ENSP00000458886 ENST00000574369	I3L1J4 [Direct mapping] Clusterin-associated protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005813 [centrosome] GO:0005929 [cilium] GO:0030992 [intraciliary transport particle B] GO:0042384 [cilium assembly] Show all	201 aa 23.7 kDa	No	0
CLUAP1-009 ENSP00000461063 ENST00000576117	I3L487 [Direct mapping] Clusterin-associated protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005813 [centrosome] GO:0005929 [cilium] GO:0030992 [intraciliary transport particle B] GO:0042384 [cilium assembly] Show all	121 aa 14 kDa	No	0
CLUAP1-010 ENSP00000458513 ENST00000574551	I3L121 [Direct mapping] Clusterin-associated protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005654 [nucleoplasm] GO:0005813 [centrosome] GO:0005929 [cilium] GO:0030992 [intraciliary transport particle B] GO:0042384 [cilium assembly] GO:0043231 [intracellular membrane-bounded organelle] Show all	151 aa 18.1 kDa	No	0

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The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.