Expression of TMEM87A in cancer - Summary - The Human Protein Atlas

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TMEM87A

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TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	TMEM87A
Gene description	Transmembrane protein 87A
Protein class	Predicted intracellular proteins Predicted membrane proteins Predicted secreted proteins
Predicted localization	Intracellular,Membrane,Secreted
Number of transcripts	9
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression with a granular pattern.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining consistent with RNA expression data. Paired antibodies with high similarity supports the protein expression profile.
Reliability score	Supported based on 2 antibodies. HPA018104 , HPA018189
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA018104	HPA018189

GENE INFORMATION
Gene name	TMEM87A (HGNC Symbol)
Synonyms	DKFZP564G2022
Description	Transmembrane protein 87A (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q15.1
Chromosome location (bp)	42210452 - 42273663
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000103978 (version 83.38)
Entrez gene	25963
UniProt	Q8NBN3 (UniProt - Evidence at protein level)
neXtProt	NX_Q8NBN3
Antibodypedia	TMEM87A antibodies

PROTEIN BROWSER

TMEM87A-001	TMEM87A-002	TMEM87A-005	TMEM87A-006	TMEM87A-007	TMEM87A-008	TMEM87A-009	TMEM87A-010	TMEM87A-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
TMEM87A-001 ENSP00000374484 ENST00000389834	Q8NBN3 [Direct mapping] Transmembrane protein 87A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	555 aa 63.4 kDa	Yes	7
TMEM87A-002 ENSP00000305894 ENST00000307216	Q8NBN3 [Direct mapping] Transmembrane protein 87A Show all	THUMBUP predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	181 aa 20.5 kDa	Yes	0
TMEM87A-005 ENSP00000456940 ENST00000568432	H3BSZ0 [Direct mapping] Transmembrane protein 87A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		40 aa 4.6 kDa	No	0
TMEM87A-006 ENSP00000454539 ENST00000568400	H3BMU0 [Direct mapping] Transmembrane protein 87A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	170 aa 19.6 kDa	No	2
TMEM87A-007 ENSP00000454278 ENST00000566474	H3BM87 [Direct mapping] Transmembrane protein 87A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	39 aa 4.5 kDa	No	0
TMEM87A-008 ENSP00000455343 ENST00000563371	H3BPJ4 [Direct mapping] Transmembrane protein 87A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	110 aa 12.7 kDa	No	1
TMEM87A-009 ENSP00000457874 ENST00000561578	H3BUZ1 [Direct mapping] Transmembrane protein 87A Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	88 aa 10 kDa	No	0
TMEM87A-010 ENSP00000457308 ENST00000566014	H3BTS6 [Direct mapping] Transmembrane protein 87A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 5TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	195 aa 22.1 kDa	No	5
TMEM87A-201 ENSP00000405379 ENST00000448392	Q8NBN3 [Direct mapping] Transmembrane protein 87A Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 7TM proteins predicted by MDM Protein evidence (Ezkurdia et al 2014) Show all	GO:0016021 [integral component of membrane] Show all	494 aa 56.8 kDa	No	7

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The Human Protein Atlas

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