Expression of DTWD1 in cancer - Summary - The Human Protein Atlas

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DTWD1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	DTWD1
Gene description	DTW domain containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification. Presumed off target binding observed and disregarded.
Reliability score	Uncertain based on 1 antibody. HPA042214
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA042214

GENE INFORMATION
Gene name	DTWD1 (HGNC Symbol)
Synonyms	MDS009, MGC111207
Description	DTW domain containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	15
Cytoband	q21.2
Chromosome location (bp)	49620980 - 49656232
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000104047 (version 83.38)
Entrez gene	56986
UniProt	Q8N5C7 (UniProt - Evidence at protein level)
neXtProt	NX_Q8N5C7
Antibodypedia	DTWD1 antibodies

PROTEIN BROWSER

DTWD1-001	DTWD1-002	DTWD1-004	DTWD1-008	DTWD1-009	DTWD1-010

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
DTWD1-001 ENSP00000251250 ENST00000251250	Q8N5C7 [Direct mapping] DTW domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		304 aa 35.2 kDa	No	0
DTWD1-002 ENSP00000453529 ENST00000558653	Q8N5C7 [Direct mapping] DTW domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		304 aa 35.2 kDa	No	0
DTWD1-004 ENSP00000385399 ENST00000403028	Q8N5C7 [Direct mapping] DTW domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		304 aa 35.2 kDa	No	0
DTWD1-008 ENSP00000453071 ENST00000559164	H0YL61 [Direct mapping] DTW domain-containing protein 1 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		193 aa 21.8 kDa	No	0
DTWD1-009 ENSP00000453649 ENST00000560632	H0YML0 [Direct mapping] DTW domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		152 aa 17.1 kDa	No	0
DTWD1-010 ENSP00000452685 ENST00000559405	H0YK73 [Direct mapping] DTW domain-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		94 aa 10.6 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.