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Cancer tissues showed weak to moderate cytoplasmic positivity. Cholangiocarcinomas and few cases of pancreatic and gastric cancers showed strong staining. Endometrial cancers, malignant gliomas, lymphomas and melanomas were generally negative.
GENE INFORMATION
Gene name
TRPA1 (HGNC Symbol)
Synonyms
ANKTM1
Description
Transient receptor potential cation channel, subfamily A, member 1 (HGNC Symbol)
Entrez gene summary
The structure of the protein encoded by this gene is highly related to both the protein ankyrin and transmembrane proteins. The specific function of this protein has not yet been determined; however, studies indicate the function may involve a role in signal transduction and growth control. [provided by RefSeq, Jul 2008]