Expression of GML in cancer - Summary - The Human Protein Atlas

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GML

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	GML
Gene description	Glycosylphosphatidylinositol anchored molecule like
Protein class	Predicted secreted proteins
Predicted localization	Secreted
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Tissue enriched (adrenal gland)

Protein evidence

Evidence at transcript level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	GML (HGNC Symbol)
Synonyms	LY6DL
Description	Glycosylphosphatidylinositol anchored molecule like (HGNC Symbol)
Entrez gene summary
Chromosome	8
Cytoband	q24.3
Chromosome location (bp)	142834247 - 142916506
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000104499 (version 83.38)
Entrez gene	2765
UniProt	Q99445 (UniProt - Evidence at transcript level)
neXtProt	NX_Q99445
Antibodypedia	GML antibodies

PROTEIN BROWSER

GML-001	GML-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GML-001 ENSP00000220940 ENST00000220940	Q99445 [Direct mapping] Glycosyl-phosphatidylinositol-anchored molecule-like protein Show all	MEMSAT3 predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005622 [intracellular] GO:0005886 [plasma membrane] GO:0006915 [apoptotic process] GO:0006977 [DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest] GO:0008285 [negative regulation of cell proliferation] GO:0019898 [extrinsic component of membrane] GO:0031225 [anchored component of membrane] Show all	158 aa 17.7 kDa	Yes	0
GML-002 ENSP00000430799 ENST00000522728	E5RI31 [Direct mapping] Glycosyl-phosphatidylinositol-anchored molecule-like protein Show all	Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all		118 aa 13.1 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.