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AMH

GENERAL INFORMATION

Gene name

 AMH

Gene description

 Anti-Mullerian hormone

Protein class

 Disease related genes
Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Tissue enriched (testis)
GTEx:Tissue enhanced (testis)
FANTOM5:Tissue enriched (testis)

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enhanced (testis)
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Tissue enriched (testis)

GENE INFORMATION

Gene name

 AMH (HGNC Symbol)

Synonyms

 MIS

Description

 Anti-Mullerian hormone (HGNC Symbol)

Entrez gene summary

 Anti-Mullerian hormone is a member of the transforming growth factor-beta gene family which mediates male sexual differentiation. Anti-Mullerian hormone causes the regression of Mullerian ducts which would otherwise differentiate into the uterus and fallopian tubes. Some mutations in the anti-Mullerian hormone result in persistent Mullerian duct syndrome. [provided by RefSeq, Jul 2008]

Chromosome

 19

Cytoband

 p13.3

Chromosome location (bp)

 2249309 - 2252073

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000104899 (version 83.38)

Entrez gene

 268

UniProt

 P03971 (UniProt - Evidence at protein level)

neXtProt

 NX_P03971

Antibodypedia

 AMH antibodies

PROTEIN BROWSER
AMH-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
AMH-001
ENSP00000221496
ENST00000221496
P03971 [Direct mapping]
Muellerian-inhibiting factor
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Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Disease related genes
Protein evidence (Kim et al 2014)
Show all
GO:0001546 [preantral ovarian follicle growth]
GO:0001655 [urogenital system development]
GO:0001880 [Mullerian duct regression]
GO:0005102 [receptor binding]
GO:0005160 [transforming growth factor beta receptor binding]
GO:0005179 [hormone activity]
GO:0005515 [protein binding]
GO:0005576 [extracellular region]
GO:0005615 [extracellular space]
GO:0005737 [cytoplasm]
GO:0007267 [cell-cell signaling]
GO:0007506 [gonadal mesoderm development]
GO:0007530 [sex determination]
GO:0007548 [sex differentiation]
GO:0007568 [aging]
GO:0008083 [growth factor activity]
GO:0008406 [gonad development]
GO:0010628 [positive regulation of gene expression]
GO:0014070 [response to organic cyclic compound]
GO:0042493 [response to drug]
GO:0051092 [positive regulation of NF-kappaB transcription factor activity]
GO:2000355 [negative regulation of ovarian follicle development]
Show all
 560 aa
59.2 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.