Cell atlas - SGTA - The Human Protein Atlas

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SGTA

TISSUE

CELL

PATHOLOGY

CELL ATLAS RNA EXPRESSION HUMAN CELLS MOUSE CELLS

GENE/PROTEIN

Antibody validation

Dictionary
	Nucleoplasm

Human cell
	Nucleoplasm

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GENERAL INFORMATION
Gene name	SGTA
Gene description	Small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION
Summary	Localized to the nucleoplasm.
RNA cell category	Mixed
Protein evidence	Evidence at protein level
Main location	Localized to the Nucleoplasm (approved)
Mouse	Localized to the Nucleoplasm in mouse cells.

DATA RELIABILITY
Reliability score	Approved based on 1 antibody. HPA056309
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ASSAYS

RNA EXPRESSION OVERVIEW
RNA cell line category: Mixed Organ Origin Category Expression Alphabetical Cell lines sorted after organ of phenotypic resemblance. Cell lines sorted after biological source for establishment. Cell lines sorted after the cell line category according to Cellosaurus. Cell lines sorted on descending RNA expression. Cell lines sorted alphabetically.

HUMAN CELLS

Summary

Localized to the nucleoplasm.

Main location

Nucleoplasm (approved)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location	Single-cell variation	Cell cycle dependent variation
	HPA056309	A-431	Nucleoplasm
	HPA056309	U-2 OS	Nucleoplasm
	HPA056309	U-251 MG	Nucleoplasm

MOUSE CELLS

Main location

Nucleoplasm

Mouse gene

ENSMUSG00000004937 (version 83)


	Toggle channels	Low High G1 S G2 M N/A

Thumbnail	Antibody	Cell line	Location
	HPA056309	NIH 3T3	Nucleoplasm

GENE INFORMATION
Gene name	SGTA (HGNC Symbol)
Synonyms	SGT
Description	Small glutamine-rich tetratricopeptide repeat (TPR)-containing, alpha (HGNC Symbol)
Entrez gene summary	This gene encodes a protein which is capable of interacting with the major nonstructural protein of parvovirus H-1 and 70-kDa heat shock cognate protein; however, its function is not known. Since this transcript is expressed ubiquitously in various tissues, this protein may serve a housekeeping function. [provided by RefSeq, Jul 2008]
Chromosome	19
Cytoband	p13.3
Chromosome location (bp)	2754714 - 2783371
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000104969 (version 83.38)
Entrez gene	6449
UniProt	O43765 (UniProt - Evidence at protein level)
neXtProt	NX_O43765
Antibodypedia	SGTA antibodies

PROTEIN BROWSER

SGTA-001	SGTA-004	SGTA-006

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
SGTA-001 ENSP00000221566 ENST00000221566	O43765 [Direct mapping] Small glutamine-rich tetratricopeptide repeat-containing protein alpha Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0005737 [cytoplasm] GO:0005829 [cytosol] GO:0008150 [biological_process] GO:0016020 [membrane] GO:0016032 [viral process] GO:1903071 [positive regulation of ER-associated ubiquitin-dependent protein catabolic process] GO:1904288 [BAT3 complex binding] Show all	313 aa 34.1 kDa	No	0
SGTA-004 ENSP00000466461 ENST00000589251	K7EMD6 [Direct mapping] Small glutamine-rich tetratricopeptide repeat-containing protein alpha Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	162 aa 17.8 kDa	No	0
SGTA-006 ENSP00000468443 ENST00000587866	K7ERW5 [Direct mapping] Small glutamine-rich tetratricopeptide repeat-containing protein alpha Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		68 aa 7.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.