Expression of LILRA1 in cancer - Summary - The Human Protein Atlas

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LILRA1

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	LILRA1
Gene description	Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1
Protein class	CD markers Predicted membrane proteins Predicted secreted proteins
Predicted localization	Membrane,Secreted
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Not detected
HPA (normal tissue):	Not detected

Protein evidence

Evidence at transcript level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	LILRA1 (HGNC Symbol)
Synonyms	CD85i, LIR-6, LIR6
Description	Leukocyte immunoglobulin-like receptor, subfamily A (with TM domain), member 1 (HGNC Symbol)
Entrez gene summary	This gene encodes an activating member of the leukocyte immunoglobulin-like receptor (LIR) family, which is found in a gene cluster at chromosomal region 19q13.4. The encoded protein is predominantly expressed in B cells, interacts with major histocompatibility complex class I ligands, and contributes to the regulation of immune responses. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, May 2013]
Chromosome	19
Cytoband	q13.42
Chromosome location (bp)	54573879 - 54602090
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000104974 (version 83.38)
Entrez gene	11024
UniProt	O75019 (UniProt - Evidence at transcript level)
neXtProt	NX_O75019
Antibodypedia	LILRA1 antibodies

PROTEIN BROWSER

LILRA1-001	LILRA1-002	LILRA1-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
LILRA1-001 ENSP00000251372 ENST00000251372	O75019 [Direct mapping] Leukocyte immunoglobulin-like receptor subfamily A member 1 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0002250 [adaptive immune response] GO:0003823 [antigen binding] GO:0004888 [transmembrane signaling receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0006952 [defense response] GO:0007166 [cell surface receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0050776 [regulation of immune response] Show all	489 aa 53.3 kDa	Yes	1
LILRA1-002 ENSP00000413715 ENST00000453777	O75019 [Direct mapping] Leukocyte immunoglobulin-like receptor subfamily A member 1 Show all	CD markers Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0002250 [adaptive immune response] GO:0003823 [antigen binding] GO:0004888 [transmembrane signaling receptor activity] GO:0005515 [protein binding] GO:0005886 [plasma membrane] GO:0006952 [defense response] GO:0007166 [cell surface receptor signaling pathway] GO:0016021 [integral component of membrane] GO:0050776 [regulation of immune response] Show all	289 aa 31.7 kDa	Yes	1
LILRA1-201 ENSP00000479482 ENST00000618665	A0A087WVJ8 [Direct mapping] Leukocyte immunoglobulin-like receptor subfamily A member 1 Show all	MEMSAT3 predicted membrane proteins Predicted secreted proteins Secreted proteins predicted by MDSEC SignalP predicted secreted proteins Phobius predicted secreted proteins SPOCTOPUS predicted secreted proteins Show all	GO:0005515 [protein binding] Show all	439 aa 47.8 kDa	Yes	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.