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TIMM44

GENERAL INFORMATION

Gene name

 TIMM44

Gene description

 Translocase of inner mitochondrial membrane 44 homolog (yeast)

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Ubiquitous granular cytoplasmic expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 1 antibody.
HPA043052
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA043052

GENE INFORMATION

Gene name

 TIMM44 (HGNC Symbol)

Synonyms

 TIM44

Description

 Translocase of inner mitochondrial membrane 44 homolog (yeast) (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 p13.2

Chromosome location (bp)

 7926718 - 7943920

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000104980 (version 83.38)

Entrez gene

 10469

UniProt

 O43615 (UniProt - Evidence at protein level)

neXtProt

 NX_O43615

Antibodypedia

 TIMM44 antibodies

PROTEIN BROWSER
TIMM44-001
TIMM44-007
TIMM44-009

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TIMM44-001
ENSP00000270538
ENST00000270538
O43615 [Direct mapping]
Mitochondrial import inner membrane translocase subunit TIM44
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005739 [mitochondrion]
GO:0005743 [mitochondrial inner membrane]
GO:0005759 [mitochondrial matrix]
GO:0006626 [protein targeting to mitochondrion]
GO:0006886 [intracellular protein transport]
GO:0015450 [P-P-bond-hydrolysis-driven protein transmembrane transporter activity]
GO:0030150 [protein import into mitochondrial matrix]
GO:0044267 [cellular protein metabolic process]
GO:0051087 [chaperone binding]
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 452 aa
51.4 kDa 		No 0
TIMM44-007
ENSP00000469389
ENST00000597926
M0QXU7 [Direct mapping]
Mitochondrial import inner membrane translocase subunit TIM44
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005739 [mitochondrion]
GO:0030150 [protein import into mitochondrial matrix]
GO:0051087 [chaperone binding]
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 273 aa
31.2 kDa 		No 0
TIMM44-009
ENSP00000469273
ENST00000595565
M0QXM9 [Direct mapping]
Mitochondrial import inner membrane translocase subunit TIM44
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0005737 [cytoplasm]
GO:0030150 [protein import into mitochondrial matrix]
GO:0051087 [chaperone binding]
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 133 aa
15.2 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.