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RAB3D

GENERAL INFORMATION

Gene name

 RAB3D

Gene description

 RAB3D, member RAS oncogene family

Protein class

 Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Cell line enhanced (SK-BR-3)
HPA (normal tissue):Tissue enhanced (skin)

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 Cytoplasmic expression in most tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

 Approved based on 1 antibody.
CAB018067
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PROGNOSTIC SUMMARY
Prognostic marker in glioma (unfavourable).
Glioma p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
CAB018067

GENE INFORMATION

Gene name

 RAB3D (HGNC Symbol)

Synonyms

 D2-2, GOV, RAB16, RAD3D

Description

 RAB3D, member RAS oncogene family (HGNC Symbol)

Entrez gene summary

Chromosome

 19

Cytoband

 p13.2

Chromosome location (bp)

 11322046 - 11346270

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000105514 (version 83.38)

Entrez gene

 9545

UniProt

 O95716 (UniProt - Evidence at protein level)

neXtProt

 NX_O95716

Antibodypedia

 RAB3D antibodies

PROTEIN BROWSER
RAB3D-001
RAB3D-002

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RAB3D-001
ENSP00000222120
ENST00000222120
O95716 [Direct mapping]
Ras-related protein Rab-3D
A0A024R7G2 [Target identity:100%; Query identity:100%]
RAB3D, member RAS oncogene family, isoform CRA_b
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Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0005515 [protein binding]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005739 [mitochondrion]
GO:0005768 [endosome]
GO:0005886 [plasma membrane]
GO:0006886 [intracellular protein transport]
GO:0006904 [vesicle docking involved in exocytosis]
GO:0006913 [nucleocytoplasmic transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0008021 [synaptic vesicle]
GO:0009306 [protein secretion]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0017157 [regulation of exocytosis]
GO:0018125 [peptidyl-cysteine methylation]
GO:0030133 [transport vesicle]
GO:0030667 [secretory granule membrane]
GO:0031489 [myosin V binding]
GO:0032482 [Rab protein signal transduction]
GO:0042588 [zymogen granule]
GO:0051020 [GTPase binding]
GO:0070062 [extracellular exosome]
GO:1903307 [positive regulation of regulated secretory pathway]
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 219 aa
24.3 kDa 		No 0
RAB3D-002
ENSP00000466000
ENST00000589655
O95716 [Direct mapping]
Ras-related protein Rab-3D
A0A024R7G2 [Target identity:100%; Query identity:100%]
RAB3D, member RAS oncogene family, isoform CRA_b
Show all
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0003924 [GTPase activity]
GO:0005525 [GTP binding]
GO:0005622 [intracellular]
GO:0005768 [endosome]
GO:0005886 [plasma membrane]
GO:0006886 [intracellular protein transport]
GO:0006904 [vesicle docking involved in exocytosis]
GO:0006913 [nucleocytoplasmic transport]
GO:0007165 [signal transduction]
GO:0007264 [small GTPase mediated signal transduction]
GO:0008021 [synaptic vesicle]
GO:0009306 [protein secretion]
GO:0015031 [protein transport]
GO:0016020 [membrane]
GO:0016079 [synaptic vesicle exocytosis]
GO:0030667 [secretory granule membrane]
GO:0031489 [myosin V binding]
GO:0032482 [Rab protein signal transduction]
GO:0070062 [extracellular exosome]
GO:1903307 [positive regulation of regulated secretory pathway]
Show all
 219 aa
24.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.