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CACNG7

GENERAL INFORMATION

Gene name

 CACNG7

Gene description

 Calcium channel, voltage-dependent, gamma subunit 7

Protein class

 Predicted membrane proteins
Transporters

Predicted localization

 Membrane

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Tissue enriched (glioma)
HPA (cell line):Cell line enhanced (AF22, HMC-1, SH-SY5Y)
HPA (normal tissue):Tissue enriched (cerebral cortex)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Tissue enriched (glioma)

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 CACNG7

Synonyms

Description

 Calcium channel, voltage-dependent, gamma subunit 7 (HGNC Symbol)

Entrez gene summary

 The protein encoded by this gene is a type II transmembrane AMPA receptor regulatory protein (TARP). TARPs regulate both trafficking and channel gating of the AMPA receptors. This gene is part of a functionally diverse eight-member protein subfamily of the PMP-22/EMP/MP20 family and is located in a cluster with two family members, a type I TARP and a calcium channel gamma subunit. [provided by RefSeq, Dec 2010]

Chromosome

 19

Cytoband

 q13.42

Chromosome location (bp)

 53909335 - 53943941

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000105605 (version 83.38)

Entrez gene

 59284

UniProt

 P62955 (UniProt - Evidence at transcript level)

neXtProt

 NX_P62955

Antibodypedia

 CACNG7 antibodies

PROTEIN BROWSER
CACNG7-001
CACNG7-002
CACNG7-004

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
CACNG7-001
ENSP00000375647
ENST00000391767
P62955 [Direct mapping]
Voltage-dependent calcium channel gamma-7 subunit
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Transporters
   Accessory Factors Involved in Transport
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
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GO:0005245 [voltage-gated calcium channel activity]
GO:0005891 [voltage-gated calcium channel complex]
GO:0006816 [calcium ion transport]
GO:0016021 [integral component of membrane]
GO:0016247 [channel regulator activity]
GO:0019226 [transmission of nerve impulse]
GO:0032281 [AMPA glutamate receptor complex]
GO:0070588 [calcium ion transmembrane transport]
GO:2000311 [regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity]
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 275 aa
31 kDa 		No 3
CACNG7-002
ENSP00000375646
ENST00000391766
A0A0C4DFY2 [Direct mapping]
Voltage-dependent calcium channel gamma-7 subunit
Show all
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Show all
GO:0006816 [calcium ion transport]
GO:0016021 [integral component of membrane]
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 198 aa
22 kDa 		No 3
CACNG7-004
ENSP00000222212
ENST00000222212
P62955 [Direct mapping]
Voltage-dependent calcium channel gamma-7 subunit
Show all
Transporters
   Accessory Factors Involved in Transport
Predicted membrane proteins
   Prediction method-based
   Membrane proteins predicted by MDM
   MEMSAT3 predicted membrane proteins
   MEMSAT-SVM predicted membrane proteins
   Phobius predicted membrane proteins
   SCAMPI predicted membrane proteins
   SPOCTOPUS predicted membrane proteins
   THUMBUP predicted membrane proteins
   TMHMM predicted membrane proteins
   # TM segments-based
   3TM proteins predicted by MDM
Protein evidence (Kim et al 2014)
Show all
GO:0005245 [voltage-gated calcium channel activity]
GO:0005891 [voltage-gated calcium channel complex]
GO:0006816 [calcium ion transport]
GO:0016021 [integral component of membrane]
GO:0016247 [channel regulator activity]
GO:0019226 [transmission of nerve impulse]
GO:0032281 [AMPA glutamate receptor complex]
GO:0070588 [calcium ion transmembrane transport]
GO:2000311 [regulation of alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionate selective glutamate receptor activity]
Show all
 275 aa
31 kDa 		No 3

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.