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Colorectal, ovarian, cervical and testicular cancers along with several urothelial, pancreatic, skin and thyroid cancers displayed weak to moderate nuclear positivity. Weak to moderate cytoplasmic positivity was observed in liver cancers. Remaining cancer tissues were in general negative.
P55199 [Direct mapping] RNA polymerase II elongation factor ELL
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Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Disease related genes Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014)
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GO:0001701 [in utero embryonic development] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0006366 [transcription from RNA polymerase II promoter] GO:0006368 [transcription elongation from RNA polymerase II promoter] GO:0008023 [transcription elongation factor complex] GO:0010467 [gene expression] GO:0010923 [negative regulation of phosphatase activity] GO:0015030 [Cajal body] GO:0016032 [viral process] GO:0016607 [nuclear speck] GO:0019902 [phosphatase binding] GO:0032786 [positive regulation of DNA-templated transcription, elongation] GO:0032968 [positive regulation of transcription elongation from RNA polymerase II promoter] GO:0035327 [transcriptionally active chromatin] GO:0035363 [histone locus body] GO:0042795 [snRNA transcription from RNA polymerase II promoter] GO:0042796 [snRNA transcription from RNA polymerase III promoter] GO:0045945 [positive regulation of transcription from RNA polymerase III promoter] GO:0050434 [positive regulation of viral transcription]
U3KQ90 [Direct mapping] RNA polymerase II elongation factor ELL
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Predicted intracellular proteins Cancer-related genes COSMIC somatic mutations in cancer genes COSMIC Somatic Mutations COSMIC Translocations Protein evidence (Ezkurdia et al 2014)
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GO:0006368 [transcription elongation from RNA polymerase II promoter] GO:0008023 [transcription elongation factor complex] GO:0042795 [snRNA transcription from RNA polymerase II promoter]