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USF2

GENERAL INFORMATION

Gene name

 USF2

Gene description

 Upstream transcription factor 2, c-fos interacting

Protein class

 Predicted intracellular proteins
Transcription factors

Predicted localization

 Intracellular

Number of transcripts

 9
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

DATA RELIABILITY

Reliability score

 Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
N/A
Hippocampus
N/A
N/A
Caudate
N/A
N/A
Cerebellum
N/A
N/A
Endocrine tissues
N/A
Bone marrow & immune system
N/A
Appendix
N/A
Tonsil
N/A
Spleen
N/A
Muscle tissues
N/A
Lung
N/A
Nasopharynx
N/A
N/A
Bronchus
N/A
N/A
Lung
N/A
Liver & gallbladder
N/A
Liver
N/A
Pancreas
N/A
Pancreas
N/A
Gastrointestinal tract
N/A
Oral mucosa
N/A
N/A
Esophagus
N/A
Stomach
N/A
Duodenum
N/A
Colon
N/A
Rectum
N/A
Kidney & urinary bladder
N/A
Kidney
N/A
Male tissues
N/A
Testis
N/A
Prostate
N/A
Female tissues
N/A
Breast
N/A
Vagina
N/A
N/A
Ovary
N/A
Placenta
N/A
Adipose & soft tissue
N/A
Soft tissue
N/A
N/A
Skin
N/A
Skin
N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 USF2 (HGNC Symbol)

Synonyms

 bHLHb12, FIP

Description

 Upstream transcription factor 2, c-fos interacting (HGNC Symbol)

Entrez gene summary

 This gene encodes a member of the basic helix-loop-helix leucine zipper family, and can function as a cellular transcription factor. The encoded protein can activate transcription through pyrimidine-rich initiator (Inr) elements and E-box motifs. Two transcript variants encoding distinct isoforms have been identified for this gene. [provided by RefSeq, Jul 2008]

Chromosome

 19

Cytoband

 q13.12

Chromosome location (bp)

 35268978 - 35279821

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000105698 (version 83.38)

Entrez gene

 7392

UniProt

 Q15853 (UniProt - Evidence at protein level)

neXtProt

 NX_Q15853

Antibodypedia

 USF2 antibodies

PROTEIN BROWSER
USF2-001
USF2-002
USF2-004
USF2-005
USF2-006
USF2-008
USF2-009
USF2-010
USF2-013

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
USF2-001
ENSP00000340633
ENST00000343550
Q15853 [Direct mapping]
Upstream stimulatory factor 2
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000430 [regulation of transcription from RNA polymerase II promoter by glucose]
GO:0000432 [positive regulation of transcription from RNA polymerase II promoter by glucose]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003705 [transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0019086 [late viral transcription]
GO:0042803 [protein homodimerization activity]
GO:0043425 [bHLH transcription factor binding]
GO:0043565 [sequence-specific DNA binding]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0055088 [lipid homeostasis]
Show all
 279 aa
30.6 kDa 		No 0
USF2-002
ENSP00000368429
ENST00000379134
Q15853 [Direct mapping]
Upstream stimulatory factor 2
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000430 [regulation of transcription from RNA polymerase II promoter by glucose]
GO:0000432 [positive regulation of transcription from RNA polymerase II promoter by glucose]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003705 [transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0019086 [late viral transcription]
GO:0042803 [protein homodimerization activity]
GO:0043425 [bHLH transcription factor binding]
GO:0043565 [sequence-specific DNA binding]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0055088 [lipid homeostasis]
Show all
 215 aa
24 kDa 		No 0
USF2-004
ENSP00000471099
ENST00000595068
Q15853 [Direct mapping]
Upstream stimulatory factor 2
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000430 [regulation of transcription from RNA polymerase II promoter by glucose]
GO:0000432 [positive regulation of transcription from RNA polymerase II promoter by glucose]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003705 [transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0019086 [late viral transcription]
GO:0042803 [protein homodimerization activity]
GO:0043425 [bHLH transcription factor binding]
GO:0043565 [sequence-specific DNA binding]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0055088 [lipid homeostasis]
Show all
 338 aa
36.2 kDa 		No 0
USF2-005
ENSP00000471511
ENST00000594064
B4DLJ1 [Direct mapping]
Upstream stimulatory factor 2; cDNA FLJ60670, highly similar to Upstream stimulatory factor 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0046983 [protein dimerization activity]
Show all
 349 aa
36.6 kDa 		No 0
USF2-006
ENSP00000471775
ENST00000596380
M0R1C6 [Direct mapping]
Upstream stimulatory factor 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0046983 [protein dimerization activity]
Show all
 143 aa
15.7 kDa 		No 0
USF2-008
ENSP00000470081
ENST00000599625
M0QYU7 [Direct mapping]
Upstream stimulatory factor 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0046983 [protein dimerization activity]
Show all
 149 aa
17.2 kDa 		No 0
USF2-009
ENSP00000469585
ENST00000598058
M0QY46 [Direct mapping]
Upstream stimulatory factor 2
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
 170 aa
16.6 kDa 		No 0
USF2-010
ENSP00000469364
ENST00000599471
M0QXT0 [Direct mapping]
Upstream stimulatory factor 2
Show all
   SCAMPI predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005654 [nucleoplasm]
GO:0046983 [protein dimerization activity]
Show all
 253 aa
28.1 kDa 		No 0
USF2-013
ENSP00000222305
ENST00000222305
Q15853 [Direct mapping]
Upstream stimulatory factor 2
Show all
Predicted intracellular proteins
Transcription factors
   Basic domains
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000430 [regulation of transcription from RNA polymerase II promoter by glucose]
GO:0000432 [positive regulation of transcription from RNA polymerase II promoter by glucose]
GO:0003677 [DNA binding]
GO:0003700 [transcription factor activity, sequence-specific DNA binding]
GO:0003705 [transcription factor activity, RNA polymerase II distal enhancer sequence-specific binding]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005654 [nucleoplasm]
GO:0006357 [regulation of transcription from RNA polymerase II promoter]
GO:0006366 [transcription from RNA polymerase II promoter]
GO:0007595 [lactation]
GO:0019086 [late viral transcription]
GO:0042803 [protein homodimerization activity]
GO:0043425 [bHLH transcription factor binding]
GO:0043565 [sequence-specific DNA binding]
GO:0045893 [positive regulation of transcription, DNA-templated]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046982 [protein heterodimerization activity]
GO:0046983 [protein dimerization activity]
GO:0055088 [lipid homeostasis]
Show all
 346 aa
37 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.