Expression of KXD1 in cancer - Summary - The Human Protein Atlas

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KXD1

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	KXD1
Gene description	KxDL motif containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	15
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA041507 , HPA041599
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable) and liver cancer (unfavourable).
Renal cancer p<0.001 Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA041507	HPA041599

GENE INFORMATION
Gene name	KXD1 (HGNC Symbol)
Synonyms	BORCS4, C19orf50, FLJ25480, KXDL, MGC2749
Description	KxDL motif containing 1 (HGNC Symbol)
Entrez gene summary
Chromosome	19
Cytoband	p13.11
Chromosome location (bp)	18557762 - 18569387
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000105700 (version 83.38)
Entrez gene	79036
UniProt	Q9BQD3 (UniProt - Evidence at protein level)
neXtProt	NX_Q9BQD3
Antibodypedia	KXD1 antibodies

PROTEIN BROWSER

KXD1-001	KXD1-003	KXD1-004	KXD1-005	KXD1-007	KXD1-008	KXD1-009	KXD1-010	KXD1-011	KXD1-012	KXD1-013	KXD1-014	KXD1-015	KXD1-201	KXD1-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KXD1-001 ENSP00000222307 ENST00000222307	Q9BQD3 [Direct mapping] KxDL motif-containing protein 1 A0A024R7M2 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0016192 [vesicle-mediated transport] GO:0031083 [BLOC-1 complex] Show all	176 aa 19.7 kDa	No	0
KXD1-003 ENSP00000472836 ENST00000602094	Q9BQD3 [Direct mapping] KxDL motif-containing protein 1 A0A024R7M2 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0016192 [vesicle-mediated transport] GO:0031083 [BLOC-1 complex] Show all	176 aa 19.7 kDa	No	0
KXD1-004 ENSP00000472268 ENST00000600372	M0R228 [Direct mapping] KxDL motif-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		132 aa 15.1 kDa	No	0
KXD1-005 ENSP00000469648 ENST00000601630	M0QY77 [Direct mapping] KxDL motif-containing protein 1 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		195 aa 21.9 kDa	No	0
KXD1-007 ENSP00000468857 ENST00000598830	M0R2G3 [Direct mapping] KxDL motif-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		128 aa 14.6 kDa	No	0
KXD1-008 ENSP00000472535 ENST00000599000	M0R2G3 [Direct mapping] KxDL motif-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		128 aa 14.6 kDa	No	0
KXD1-009 ENSP00000468949 ENST00000595870	M0QX74 [Direct mapping] KxDL motif-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		136 aa 15.5 kDa	No	0
KXD1-010 ENSP00000469288 ENST00000596785	M0QXN9 [Direct mapping] KxDL motif-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		74 aa 8.6 kDa	No	0
KXD1-011 ENSP00000473057 ENST00000596244		Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		5 aa 0.6 kDa	No	0
KXD1-012 ENSP00000468990 ENST00000599319	Q9BQD3 [Direct mapping] KxDL motif-containing protein 1 A0A024R7M2 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0016192 [vesicle-mediated transport] GO:0031083 [BLOC-1 complex] Show all	176 aa 19.7 kDa	No	0
KXD1-013 ENSP00000469294 ENST00000597438	M0QXP3 [Direct mapping] KxDL motif-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		167 aa 18.7 kDa	No	0
KXD1-014 ENSP00000471127 ENST00000600099	M0R0B4 [Direct mapping] KxDL motif-containing protein 1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		85 aa 9.8 kDa	No	0
KXD1-015 ENSP00000471554 ENST00000595073	Q9BQD3 [Direct mapping] KxDL motif-containing protein 1 A0A024R7M2 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0016192 [vesicle-mediated transport] GO:0031083 [BLOC-1 complex] Show all	176 aa 19.7 kDa	No	0
KXD1-201 ENSP00000438903 ENST00000539106	Q9BQD3 [Direct mapping] KxDL motif-containing protein 1 A0A024R7M2 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0016192 [vesicle-mediated transport] GO:0031083 [BLOC-1 complex] Show all	176 aa 19.7 kDa	No	0
KXD1-202 ENSP00000443549 ENST00000540691	Q9BQD3 [Direct mapping] KxDL motif-containing protein 1 A0A024R7M2 [Target identity:100%; Query identity:100%] Uncharacterized protein Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] GO:0016192 [vesicle-mediated transport] GO:0031083 [BLOC-1 complex] Show all	176 aa 19.7 kDa	No	0

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The Human Protein Atlas

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