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A majority of cancers showed weak staining or were negative. Skin cancers showed moderate to strong cytoplasmic immunoreactivity while several cases of lymphomas and female genital cancers displayed moderate positivity.
GENE INFORMATION
Gene name
GTPBP10 (HGNC Symbol)
Synonyms
DKFZP686A10121, FLJ38242
Description
GTP-binding protein 10 (putative) (HGNC Symbol)
Entrez gene summary
Small G proteins, such as GTPBP10, act as molecular switches that play crucial roles in the regulation of fundamental cellular processes such as protein synthesis, nuclear transport, membrane trafficking, and signal transduction (Hirano et al., 2006 [PubMed 17054726]).[supplied by OMIM, Mar 2008]