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Most cancer tissues showed moderate to strong cytoplasmic immunoreactivity. Strongest staining was observed in colorectal cancers, breast cancers and melanomas.
GENE INFORMATION
Gene name
SSBP1 (HGNC Symbol)
Synonyms
mtSSB, SSBP
Description
Single-stranded DNA binding protein 1, mitochondrial (HGNC Symbol)
Entrez gene summary
SSBP1 is a housekeeping gene involved in mitochondrial biogenesis (Tiranti et al., 1995 [PubMed 7789991]). It is also a subunit of a single-stranded DNA (ssDNA)-binding complex involved in the maintenance of genome stability (Huang et al., 2009) [PubMed 19683501].[supplied by OMIM, Feb 2010]