Tissue expression of MOGAT3 - Summary - The Human Protein Atlas

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MOGAT3

TISSUE

CELL

PATHOLOGY

TISSUE ATLAS PRIMARY DATA

GENE/PROTEIN

Antibody validation

Dictionary


Tissue proteome

GENERAL INFORMATION
Gene name	MOGAT3
Gene description	Monoacylglycerol O-acyltransferase 3
Protein class	Enzymes Predicted membrane proteins
Predicted localization	Membrane
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Group enriched (colon, duodenum, rectum, small intestine)
GTEx:	Group enriched (colon, liver, small intestine)
FANTOM5:	Group enriched (colon, small intestine)

Protein evidence

Evidence at protein level

Protein expression

General cytoplasmic expression.

DATA RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data.
Reliability score	Uncertain based on 1 antibody. HPA011940
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RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

Cerebral cortex

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

Thyroid gland

Parathyroid gland

Adrenal gland

Bone marrow & immune system

Appendix

Bone marrow

Lymph node

Tonsil

Spleen

Muscle tissues

Heart muscle

Skeletal muscle

Smooth muscle

Lung

Nasopharynx

N/A

Bronchus

N/A

Lung

Liver & gallbladder

Liver

Gallbladder

Pancreas

Pancreas

Gastrointestinal tract

Oral mucosa

N/A

Salivary gland

Esophagus

Stomach

Duodenum

Small intestine

Colon

Rectum

Kidney & urinary bladder

Kidney

Urinary bladder

Male tissues

Testis

Epididymis

Prostate

Seminal vesicle

Female tissues

Breast

Vagina

N/A

Cervix, uterine

Endometrium

Fallopian tube

Ovary

Placenta

Adipose & soft tissue

Adipose tissue

Soft tissue

N/A

Skin

Skin

Cerebral cortex

Small intestine

PROTEIN EXPRESSION OVERVIEW
Organ Expression Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Group enriched (colon, duodenum, rectum, small intestine)
GTEx dataset Organ Expression Alphabetical RNA tissue category: Group enriched (colon, liver, small intestine)
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Group enriched (colon, small intestine)

GENE INFORMATION
Gene name	MOGAT3 (HGNC Symbol)
Synonyms	DC7, MGAT3
Description	Monoacylglycerol O-acyltransferase 3 (HGNC Symbol)
Entrez gene summary	Acyl-CoA:monoacylglycerol acyltransferase (MOGAT; EC 2.3.1.22) catalyzes the synthesis of diacylglycerol from 2-monoacylglycerol and fatty acyl-CoA (Cheng et al., 2003 [PubMed 12618427]).[supplied by OMIM, Mar 2008]
Chromosome	7
Cytoband	q22.1
Chromosome location (bp)	101195007 - 101201021
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000106384 (version 83.38)
Entrez gene	346606
UniProt	Q86VF5 (UniProt - Evidence at protein level)
neXtProt	NX_Q86VF5
Antibodypedia	MOGAT3 antibodies

PROTEIN BROWSER

MOGAT3-001	MOGAT3-002	MOGAT3-003

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MOGAT3-001 ENSP00000223114 ENST00000223114	Q86VF5 [Direct mapping] 2-acylglycerol O-acyltransferase 3 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0003846 [2-acylglycerol O-acyltransferase activity] GO:0004144 [diacylglycerol O-acyltransferase activity] GO:0005789 [endoplasmic reticulum membrane] GO:0006071 [glycerol metabolic process] GO:0016021 [integral component of membrane] GO:0016747 [transferase activity, transferring acyl groups other than amino-acyl groups] GO:0019432 [triglyceride biosynthetic process] Show all	341 aa 38.7 kDa	No	1
MOGAT3-002 ENSP00000368734 ENST00000379423	Q86VF5 [Direct mapping] 2-acylglycerol O-acyltransferase 3 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0003846 [2-acylglycerol O-acyltransferase activity] GO:0004144 [diacylglycerol O-acyltransferase activity] GO:0005789 [endoplasmic reticulum membrane] GO:0006071 [glycerol metabolic process] GO:0016021 [integral component of membrane] GO:0016747 [transferase activity, transferring acyl groups other than amino-acyl groups] GO:0019432 [triglyceride biosynthetic process] Show all	281 aa 31.5 kDa	No	1
MOGAT3-003 ENSP00000403756 ENST00000440203	Q86VF5 [Direct mapping] 2-acylglycerol O-acyltransferase 3 Show all	Enzymes ENZYME proteins Transferases Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins TMHMM predicted membrane proteins # TM segments-based 1TM proteins predicted by MDM Show all	GO:0003846 [2-acylglycerol O-acyltransferase activity] GO:0004144 [diacylglycerol O-acyltransferase activity] GO:0005789 [endoplasmic reticulum membrane] GO:0006071 [glycerol metabolic process] GO:0016021 [integral component of membrane] GO:0016747 [transferase activity, transferring acyl groups other than amino-acyl groups] GO:0019432 [triglyceride biosynthetic process] Show all	344 aa 38.4 kDa	No	1

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The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.