Expression of MYL10 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

MYL10

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	MYL10
Gene description	Myosin, light chain 10, regulatory
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Tissue enhanced (melanoma)
HPA (cell line):	Cell line enhanced (PC-3, RH-30)
HPA (normal tissue):	Not detected

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Caution, targets protein from more than one gene.
Reliability score	Uncertain based on 1 antibody. HPA019763
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Tissue enhanced (melanoma)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA019763

GENE INFORMATION
Gene name	MYL10 (HGNC Symbol)
Synonyms	MGC3479, MYLC2PL, PLRLC
Description	Myosin, light chain 10, regulatory (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	q22.1
Chromosome location (bp)	101613325 - 101629296
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000106436 (version 83.38)
Entrez gene	93408
UniProt	Q9BUA6 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9BUA6
Antibodypedia	MYL10 antibodies

PROTEIN BROWSER

MYL10-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
MYL10-001 ENSP00000223167 ENST00000223167	Q9BUA6 [Direct mapping] Myosin regulatory light chain 10 Show all	SCAMPI predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005739 [mitochondrion] GO:0005829 [cytosol] GO:0006936 [muscle contraction] Show all	226 aa 25.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.