Expression of ACTR3C in cancer - Summary - The Human Protein Atlas

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ACTR3C

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ACTR3C
Gene description	ARP3 actin-related protein 3 homolog C (yeast)
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	6
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Cell line enhanced (CAPAN-2, RT4, SiHa)
HPA (normal tissue):	Tissue enriched (parathyroid gland)

Protein evidence

Evidence at transcript level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Pending external verification. Antibody staining not consistent with RNA expression data.
Reliability score	Uncertain based on 1 antibody. HPA055957
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA055957

GENE INFORMATION
Gene name	ACTR3C (HGNC Symbol)
Synonyms	ARP11
Description	ARP3 actin-related protein 3 homolog C (yeast) (HGNC Symbol)
Entrez gene summary
Chromosome	7
Cytoband	q36.1
Chromosome location (bp)	150243916 - 150323725
Protein evidence	Evidence at transcript level (all genes)
Ensembl	ENSG00000106526 (version 83.38)
Entrez gene	653857
UniProt	Q9C0K3 (UniProt - Evidence at transcript level)
neXtProt	NX_Q9C0K3
Antibodypedia	ACTR3C antibodies

PROTEIN BROWSER

ACTR3C-001	ACTR3C-002	ACTR3C-003	ACTR3C-004	ACTR3C-201	ACTR3C-202

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ACTR3C-001 ENSP00000417997 ENST00000477367	C9J580 [Direct mapping] Actin-related protein 3C Show all	Phobius predicted membrane proteins SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Show all	GO:0005524 [ATP binding] GO:0005885 [Arp2/3 protein complex] GO:0034314 [Arp2/3 complex-mediated actin nucleation] Show all	51 aa 5.4 kDa	No	0
ACTR3C-002 ENSP00000252071 ENST00000252071	Q9C0K3 [Direct mapping] Actin-related protein 3C Show all	SignalP predicted secreted proteins Predicted intracellular proteins Show all	GO:0003674 [molecular_function] GO:0003779 [actin binding] GO:0005524 [ATP binding] GO:0005885 [Arp2/3 protein complex] GO:0008150 [biological_process] GO:0034314 [Arp2/3 complex-mediated actin nucleation] GO:0070062 [extracellular exosome] Show all	210 aa 23.7 kDa	No	0
ACTR3C-003 ENSP00000418635 ENST00000477871	C9IZN3 [Direct mapping] Actin-related protein 3C Show all	THUMBUP predicted membrane proteins Predicted intracellular proteins Show all	GO:0005524 [ATP binding] GO:0005885 [Arp2/3 protein complex] GO:0034314 [Arp2/3 complex-mediated actin nucleation] Show all	222 aa 24.3 kDa	No	0
ACTR3C-004 ENSP00000417426 ENST00000478393	H7C4J1 [Direct mapping] Actin-related protein 3C Show all	Predicted intracellular proteins Show all	GO:0005524 [ATP binding] GO:0005885 [Arp2/3 protein complex] GO:0034314 [Arp2/3 complex-mediated actin nucleation] Show all	208 aa 23.8 kDa	No	0
ACTR3C-201 ENSP00000440990 ENST00000539352	A0A0A0MTI9 [Direct mapping] Actin-related protein 3C Show all	SignalP predicted secreted proteins Predicted intracellular proteins Show all	GO:0005524 [ATP binding] GO:0005885 [Arp2/3 protein complex] GO:0034314 [Arp2/3 complex-mediated actin nucleation] Show all	189 aa 21.3 kDa	No	0
ACTR3C-202 ENSP00000481447 ENST00000613959	A0A087WY14 [Direct mapping] Actin-related protein 3C Show all	Predicted intracellular proteins Show all		24 aa 2.8 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.