Fields »
ABOUT
HELP
BLOG
TESK1

GENERAL INFORMATION

Gene name

 TESK1

Gene description

 Testis-specific kinase 1

Protein class

 Enzymes
Plasma proteins
Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable).
Liver cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 TESK1

Synonyms

Description

 Testis-specific kinase 1 (HGNC Symbol)

Entrez gene summary

 This gene product is a serine/threonine protein kinase that contains an N-terminal protein kinase domain and a C-terminal proline-rich domain. Its protein kinase domain is most closely related to those of the LIM motif-containing protein kinases (LIMKs). The encoded protein can phosphorylate myelin basic protein and histone in vitro. The testicular germ cell-specific expression and developmental pattern of expression of the mouse gene suggests that this gene plays an important role at and after the meiotic phase of spermatogenesis. [provided by RefSeq, Jul 2008]

Chromosome

 9

Cytoband

 p13.3

Chromosome location (bp)

 35605305 - 35610041

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000107140 (version 83.38)

Entrez gene

 7016

UniProt

 Q15569 (UniProt - Evidence at protein level)

neXtProt

 NX_Q15569

Antibodypedia

 TESK1 antibodies

PROTEIN BROWSER
TESK1-001
TESK1-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
TESK1-001
ENSP00000338127
ENST00000336395
Q15569 [Direct mapping]
Dual specificity testis-specific protein kinase 1
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   TKL Ser/Thr protein kinases
Predicted intracellular proteins
Plasma proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004712 [protein serine/threonine/tyrosine kinase activity]
GO:0004713 [protein tyrosine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005829 [cytosol]
GO:0006468 [protein phosphorylation]
GO:0018108 [peptidyl-tyrosine phosphorylation]
GO:0034329 [cell junction assembly]
GO:0046872 [metal ion binding]
Show all
 626 aa
67.7 kDa 		No 0
TESK1-201
ENSP00000481045
ENST00000620767
Q15569 [Direct mapping]
Dual specificity testis-specific protein kinase 1
Show all
Enzymes
   ENZYME proteins
   Transferases
   Kinases
   TKL Ser/Thr protein kinases
Predicted intracellular proteins
Plasma proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0004672 [protein kinase activity]
GO:0004674 [protein serine/threonine kinase activity]
GO:0004712 [protein serine/threonine/tyrosine kinase activity]
GO:0004713 [protein tyrosine kinase activity]
GO:0005515 [protein binding]
GO:0005524 [ATP binding]
GO:0005829 [cytosol]
GO:0006468 [protein phosphorylation]
GO:0007283 [spermatogenesis]
GO:0018108 [peptidyl-tyrosine phosphorylation]
GO:0034329 [cell junction assembly]
GO:0046872 [metal ion binding]
Show all
 626 aa
67.7 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.