Expression of ABHD17B in cancer - Summary - The Human Protein Atlas

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ABHD17B

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ABHD17B
Gene description	Abhydrolase domain containing 17B
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Secreted protein, tissue location of RNA and protein might differ and correlation is complex.
Reliability score	Uncertain based on 1 antibody. HPA047862
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA047862

GENE INFORMATION
Gene name	ABHD17B (HGNC Symbol)
Synonyms	C9orf77, CGI-67, FAM108B1
Description	Abhydrolase domain containing 17B (HGNC Symbol)
Entrez gene summary
Chromosome	9
Cytoband	q21.13
Chromosome location (bp)	71862452 - 71910931
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000107362 (version 83.38)
Entrez gene	51104
UniProt	Q5VST6 (UniProt - Evidence at protein level)
neXtProt	NX_Q5VST6
Antibodypedia	ABHD17B antibodies

PROTEIN BROWSER

ABHD17B-001	ABHD17B-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ABHD17B-001 ENSP00000366240 ENST00000377041	Q5VST6 [Direct mapping] Alpha/beta hydrolase domain-containing protein 17B Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005576 [extracellular region] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0016787 [hydrolase activity] Show all	293 aa 32.8 kDa	No	0
ABHD17B-002 ENSP00000330222 ENST00000333421	Q5VST6 [Direct mapping] Alpha/beta hydrolase domain-containing protein 17B Show all	Phobius predicted secreted proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005576 [extracellular region] GO:0008152 [metabolic process] GO:0016020 [membrane] GO:0016787 [hydrolase activity] Show all	288 aa 32.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.