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EIF3A

GENERAL INFORMATION

Gene name

 EIF3A

Gene description

 Eukaryotic translation initiation factor 3, subunit A

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 2
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Ubiquitous cytoplasmic expression.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data.

Reliability score

 Supported based on 2 antibodies.
HPA038315 , HPA038316
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 EIF3A (HGNC Symbol)

Synonyms

 EIF3, eIF3-p170, eIF3-theta, eIF3a, EIF3S10, KIAA0139, TIF32

Description

 Eukaryotic translation initiation factor 3, subunit A (HGNC Symbol)

Entrez gene summary

Chromosome

 10

Cytoband

 q26.11

Chromosome location (bp)

 119033670 - 119080823

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000107581 (version 83.38)

Entrez gene

 8661

UniProt

 Q14152 (UniProt - Evidence at protein level)

neXtProt

 NX_Q14152

Antibodypedia

 EIF3A antibodies

PROTEIN BROWSER
EIF3A-001
EIF3A-201

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
EIF3A-001
ENSP00000358140
ENST00000369144
Q14152 [Direct mapping]
Eukaryotic translation initiation factor 3 subunit A
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001731 [formation of translation preinitiation complex]
GO:0001732 [formation of cytoplasmic translation initiation complex]
GO:0003743 [translation initiation factor activity]
GO:0005198 [structural molecule activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005852 [eukaryotic translation initiation factor 3 complex]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006446 [regulation of translational initiation]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016282 [eukaryotic 43S preinitiation complex]
GO:0033290 [eukaryotic 48S preinitiation complex]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
GO:0071541 [eukaryotic translation initiation factor 3 complex, eIF3m]
Show all
 1382 aa
166.6 kDa 		No 0
EIF3A-201
ENSP00000438178
ENST00000541549
Q14152 [Direct mapping]
Eukaryotic translation initiation factor 3 subunit A
Show all
   SPOCTOPUS predicted membrane proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0001731 [formation of translation preinitiation complex]
GO:0001732 [formation of cytoplasmic translation initiation complex]
GO:0003743 [translation initiation factor activity]
GO:0005198 [structural molecule activity]
GO:0005515 [protein binding]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005852 [eukaryotic translation initiation factor 3 complex]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006446 [regulation of translational initiation]
GO:0010467 [gene expression]
GO:0016020 [membrane]
GO:0016282 [eukaryotic 43S preinitiation complex]
GO:0033290 [eukaryotic 48S preinitiation complex]
GO:0044267 [cellular protein metabolic process]
GO:0044822 [poly(A) RNA binding]
Show all
 1382 aa
166.6 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.