Tissue expression of OBFC1 - Summary - The Human Protein Atlas

GENERAL INFORMATION
Gene name	OBFC1
Gene description	Oligonucleotide/oligosaccharide-binding fold containing 1
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category

HPA:	Expressed in all
GTEx:	Expressed in all
FANTOM5:	Expressed in all

Protein evidence

Evidence at protein level

DATA RELIABILITY
Reliability score	Pending normal tissue annotation.

RNA AND PROTEIN EXPRESSION SUMMARY

RNA expression (TPM)

Protein expression (score)

Brain

N/A

Cerebral cortex

N/A

Hippocampus

N/A

Caudate

N/A

Cerebellum

N/A

Endocrine tissues

N/A

Thyroid gland

N/A

Parathyroid gland

N/A

Adrenal gland

N/A

Bone marrow & immune system

N/A

Appendix

N/A

Bone marrow

N/A

Lymph node

N/A

Tonsil

N/A

Spleen

N/A

Muscle tissues

N/A

Heart muscle

N/A

Skeletal muscle

N/A

Smooth muscle

N/A

Lung

N/A

Nasopharynx

N/A

Bronchus

N/A

Lung

N/A

Liver & gallbladder

N/A

Liver

N/A

Gallbladder

N/A

Pancreas

N/A

Pancreas

N/A

Gastrointestinal tract

N/A

Oral mucosa

N/A

Salivary gland

N/A

Esophagus

N/A

Stomach

N/A

Duodenum

N/A

Small intestine

N/A

Colon

N/A

Rectum

N/A

Kidney & urinary bladder

N/A

Kidney

N/A

Urinary bladder

N/A

Male tissues

N/A

Testis

N/A

Epididymis

N/A

Prostate

N/A

Seminal vesicle

N/A

Female tissues

N/A

Breast

N/A

Vagina

N/A

Cervix, uterine

N/A

Endometrium

N/A

Fallopian tube

N/A

Ovary

N/A

Placenta

N/A

Adipose & soft tissue

N/A

Adipose tissue

N/A

Soft tissue

N/A

Skin

N/A

Skin

N/A

PROTEIN EXPRESSION OVERVIEW
Pending normal tissue annotation.

RNA EXPRESSION OVERVIEW
HPA dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
GTEx dataset Organ Expression Alphabetical RNA tissue category: Expressed in all
FANTOM5 dataset Organ Expression Alphabetical RNA tissue category: Expressed in all

GENE INFORMATION
Gene name	OBFC1 (HGNC Symbol)
Synonyms	bA541N10.2, FLJ22559
Description	Oligonucleotide/oligosaccharide-binding fold containing 1 (HGNC Symbol)
Entrez gene summary	OBFC1 and C17ORF68 (MIM 613129) are subunits of an alpha accessory factor (AAF) that stimulates the activity of DNA polymerase-alpha-primase (see MIM 176636), the enzyme that initiates DNA replication (Casteel et al., 2009 [PubMed 19119139]). OBFC1 also appears to function in a telomere-associated complex with C17ORF68 and TEN1 (C17ORF106; MIM 613130) (Miyake et al., 2009 [PubMed 19854130]).[supplied by OMIM, Nov 2009]
Chromosome	10
Cytoband	q24.33
Chromosome location (bp)	103882542 - 103918205
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000107960 (version 83.38)
Entrez gene	79991
UniProt	Q9H668 (UniProt - Evidence at protein level)
neXtProt	NX_Q9H668
Antibodypedia	OBFC1 antibodies

PROTEIN BROWSER

OBFC1-001	OBFC1-002

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
OBFC1-001 ENSP00000224950 ENST00000224950	Q9H668 [Direct mapping] CST complex subunit STN1 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000723 [telomere maintenance] GO:0000784 [nuclear chromosome, telomeric region] GO:0003676 [nucleic acid binding] GO:0003697 [single-stranded DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0010521 [telomerase inhibitor activity] GO:0010833 [telomere maintenance via telomere lengthening] GO:0042162 [telomeric DNA binding] GO:0043047 [single-stranded telomeric DNA binding] GO:0043231 [intracellular membrane-bounded organelle] GO:0045111 [intermediate filament cytoskeleton] GO:0045740 [positive regulation of DNA replication] GO:0051974 [negative regulation of telomerase activity] GO:0070188 [Stn1-Ten1 complex] GO:1904356 [regulation of telomere maintenance via telomere lengthening] Show all	368 aa 42.1 kDa	No	0
OBFC1-002 ENSP00000358779 ENST00000369764	Q9H668 [Direct mapping] CST complex subunit STN1 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0000723 [telomere maintenance] GO:0000784 [nuclear chromosome, telomeric region] GO:0003676 [nucleic acid binding] GO:0003697 [single-stranded DNA binding] GO:0005515 [protein binding] GO:0005634 [nucleus] GO:0005654 [nucleoplasm] GO:0005730 [nucleolus] GO:0010521 [telomerase inhibitor activity] GO:0010833 [telomere maintenance via telomere lengthening] GO:0042162 [telomeric DNA binding] GO:0043047 [single-stranded telomeric DNA binding] GO:0043231 [intracellular membrane-bounded organelle] GO:0045111 [intermediate filament cytoskeleton] GO:0045740 [positive regulation of DNA replication] GO:0051974 [negative regulation of telomerase activity] GO:1904356 [regulation of telomere maintenance via telomere lengthening] Show all	368 aa 42.1 kDa	No	0