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UTP6

GENERAL INFORMATION

Gene name

 UTP6

Gene description

 UTP6, small subunit (SSU) processome component, homolog (yeast)

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 General nucleolar expression.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.

Reliability score

 Supported based on 1 antibody.
HPA025936
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable) and liver cancer (unfavourable).
Renal cancer p<0.001
Liver cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA025936

GENE INFORMATION

Gene name

 UTP6 (HGNC Symbol)

Synonyms

 C17orf40, HCA66

Description

 UTP6, small subunit (SSU) processome component, homolog (yeast) (HGNC Symbol)

Entrez gene summary

Chromosome

 17

Cytoband

 q11.2

Chromosome location (bp)

 31860899 - 31901765

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000108651 (version 83.38)

Entrez gene

 55813

UniProt

 Q9NYH9 (UniProt - Evidence at transcript level)

neXtProt

 NX_Q9NYH9

Antibodypedia

 UTP6 antibodies

PROTEIN BROWSER
UTP6-001
UTP6-007
UTP6-008

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
UTP6-001
ENSP00000261708
ENST00000261708
Q9NYH9 [Direct mapping]
U3 small nucleolar RNA-associated protein 6 homolog
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0005622 [intracellular]
GO:0005730 [nucleolus]
GO:0006396 [RNA processing]
GO:0030515 [snoRNA binding]
GO:0032040 [small-subunit processome]
GO:0034388 [Pwp2p-containing subcomplex of 90S preribosome]
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 597 aa
70.2 kDa 		No 0
UTP6-007
ENSP00000462135
ENST00000581012
J3KRR8 [Direct mapping]
U3 small nucleolar RNA-associated protein 6 homolog
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
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GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0030515 [snoRNA binding]
GO:0032040 [small-subunit processome]
GO:0034388 [Pwp2p-containing subcomplex of 90S preribosome]
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 61 aa
6.9 kDa 		No 0
UTP6-008
ENSP00000464599
ENST00000579459
J3QSA7 [Direct mapping]
U3 small nucleolar RNA-associated protein 6 homolog
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Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000462 [maturation of SSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)]
GO:0030515 [snoRNA binding]
GO:0032040 [small-subunit processome]
GO:0034388 [Pwp2p-containing subcomplex of 90S preribosome]
Show all
 29 aa
3.5 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.