Expression of KRT32 in cancer - Summary - The Human Protein Atlas

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KRT32

TISSUE

CELL

PATHOLOGY

GENERAL INFORMATION
Gene name	KRT32
Gene description	Keratin 32, type I
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Not detected
HPA (cell line):	Not detected
HPA (normal tissue):	Group enriched (esophagus, skin)

Protein evidence

Evidence at protein level

ANTIBODY IHC RELIABILITY
Reliability score	Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Not detected

PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY

GENE INFORMATION
Gene name	KRT32 (HGNC Symbol)
Synonyms	Ha-2, KRTHA2
Description	Keratin 32, type I (HGNC Symbol)
Entrez gene summary	The protein encoded by this gene is a member of the keratin gene family. As a type I hair keratin, it is an acidic protein which heterodimerizes with type II keratins to form hair and nails. The type I hair keratins are clustered in a region of chromosome 17q12-q21 and have the same direction of transcription. [provided by RefSeq, Jul 2008]
Chromosome	17
Cytoband	q21.2
Chromosome location (bp)	41459811 - 41467429
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000108759 (version 83.38)
Entrez gene	3882
UniProt	Q14532 (UniProt - Evidence at transcript level)
neXtProt	NX_Q14532
Antibodypedia	KRT32 antibodies

PROTEIN BROWSER

KRT32-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
KRT32-001 ENSP00000225899 ENST00000225899	Q14532 [Direct mapping] Keratin, type I cuticular Ha2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005198 [structural molecule activity] GO:0005882 [intermediate filament] GO:0008544 [epidermis development] GO:0070062 [extracellular exosome] Show all	448 aa 50.3 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.