Expression of CDR2L in cancer - Summary - The Human Protein Atlas

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CDR2L

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	CDR2L
Gene description	Cerebellar degeneration-related protein 2-like
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Mixed
HPA (normal tissue):	Mixed

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression in all tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 1 antibody. HPA022015
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PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA022015

GENE INFORMATION
Gene name	CDR2L (HGNC Symbol)
Synonyms	HUMPPA
Description	Cerebellar degeneration-related protein 2-like (HGNC Symbol)
Entrez gene summary
Chromosome	17
Cytoband	q25.1
Chromosome location (bp)	74987632 - 75005800
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000109089 (version 83.38)
Entrez gene	30850
UniProt	Q86X02 (UniProt - Evidence at protein level)
neXtProt	NX_Q86X02
Antibodypedia	CDR2L antibodies

PROTEIN BROWSER

CDR2L-001

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
CDR2L-001 ENSP00000336587 ENST00000337231	Q86X02 [Direct mapping] Cerebellar degeneration-related protein 2-like A0A024R8R6 [Target identity:100%; Query identity:100%] Cerebellar degeneration-related protein 2-like, isoform CRA_b Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all		465 aa 53 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.