Expression of ZNF330 in cancer - Summary - The Human Protein Atlas

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ZNF330

TISSUE

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CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ZNF330
Gene description	Zinc finger protein 330
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	4
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and nuclear expression in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly not consistent with RNA expression data. Pending external verification.
Reliability score	Uncertain based on 1 antibody. HPA015705
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PROGNOSTIC SUMMARY
Prognostic marker in prostate cancer (unfavourable) and renal cancer (favourable).
Prostate cancer p<0.001 Renal cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA015705

GENE INFORMATION
Gene name	ZNF330 (HGNC Symbol)
Synonyms	HSA6591, NOA36
Description	Zinc finger protein 330 (HGNC Symbol)
Entrez gene summary
Chromosome	4
Cytoband	q31.21
Chromosome location (bp)	141220887 - 141234697
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000109445 (version 83.38)
Entrez gene	27309
UniProt	Q9Y3S2 (UniProt - Evidence at protein level)
neXtProt	NX_Q9Y3S2
Antibodypedia	ZNF330 antibodies

PROTEIN BROWSER

ZNF330-001	ZNF330-005	ZNF330-006	ZNF330-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ZNF330-001 ENSP00000262990 ENST00000262990	Q9Y3S2 [Direct mapping] Zinc finger protein 330 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0000775 [chromosome, centromeric region] GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0008150 [biological_process] GO:0008270 [zinc ion binding] GO:0030496 [midbody] GO:0046872 [metal ion binding] Show all	320 aa 36.2 kDa	No	0
ZNF330-005 ENSP00000422599 ENST00000512809	D6RBR7 [Direct mapping] Zinc finger protein 330 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0008270 [zinc ion binding] Show all	229 aa 25.8 kDa	No	0
ZNF330-006 ENSP00000422966 ENST00000503649	D6R9C8 [Direct mapping] Zinc finger protein 330 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0008270 [zinc ion binding] Show all	140 aa 15.7 kDa	No	0
ZNF330-007 ENSP00000422251 ENST00000512738	D6R8Y9 [Direct mapping] Zinc finger protein 330 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005634 [nucleus] GO:0005730 [nucleolus] GO:0008270 [zinc ion binding] Show all	153 aa 17.2 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.