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Field

Term
Gene name

Class

Subclass

Chromosome

External id

In atlas

Reliability

Reliability

Reliability

Validation

Method

Validation

Method

Validation

Method

Validation

Location

Searches

Tissue

Cell type

Expression

Tissue

Specificity

Cell line

Specificity

Cancer

Specificity

Tissue

Detectable

Cell line

Detectable

Cancer

Detectable

Cancer

Prognosis

Category

Score

Score

Score

Antibodies

Column

 
 
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ZNF330
  • TISSUE

  • premium

    CELL

  • PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary

Level of antibody staining/expression





High
Medium
Low
Not detected

GENERAL INFORMATION

Gene name

ZNF330

Gene description

Zinc finger protein 330

Protein class

Predicted intracellular proteins

Predicted localization

Intracellular

Number of transcripts

4
SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic and nuclear expression in several tissues.

ANTIBODY IHC RELIABILITY

Data reliability
description

Antibody staining mainly not consistent with RNA expression data. Pending external verification.

Reliability score

Uncertain based on 1 antibody.
HPA015705
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PROGNOSTIC SUMMARY

Prognostic marker in prostate cancer (unfavourable) and renal cancer (favourable).
Prostate cancer p<0.001
Renal cancer p<0.001
Show all

RNA EXPRESSION OVERVIEW

TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY

HPA015705

Cancer

Cancer staining

Protein
expression of
normal tissue

Breast cancer
 
Carcinoid
 
Cervical cancer
 
 
Colorectal cancer
 
 
Endometrial cancer
 
 
Glioma
 
Head and neck cancer
 
 
Liver cancer
 
 
Lung cancer
 
 
Lymphoma
 
 
 

Cancer

Cancer staining

Protein
expression of
normal tissue

Melanoma
 
Ovarian cancer
 
Pancreatic cancer
 
Prostate cancer
 
Renal cancer
 
Skin cancer
 
Stomach cancer
 
 
Testis cancer
 
Thyroid cancer
 
Urothelial cancer
 

Staining summary

The cancer tissues showed moderate to strong cytoplasmic staining, which often was combined with additional nuclear positivity. Several cases of renal cancers were negative.

GENE INFORMATION

Gene name

ZNF330 (HGNC Symbol)

Synonyms

HSA6591, NOA36

Description

Zinc finger protein 330 (HGNC Symbol)

Entrez gene summary

Chromosome

4

Cytoband

q31.21

Chromosome location (bp)

141220887 - 141234697

Protein evidence

Evidence at protein level (all genes)

Ensembl

ENSG00000109445 (version 83.38)

Entrez gene

27309

UniProt

Q9Y3S2 (UniProt - Evidence at protein level)

neXtProt

NX_Q9Y3S2

Antibodypedia

ZNF330 antibodies

PROTEIN BROWSER

ZNF330-001
ZNF330-005
ZNF330-006
ZNF330-007

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)

ZNF330-001
ENSP00000262990
ENST00000262990
Q9Y3S2 [Direct mapping]
Zinc finger protein 330
Show all
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000775 [chromosome, centromeric region]
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0008150 [biological_process]
GO:0008270 [zinc ion binding]
GO:0030496 [midbody]
GO:0046872 [metal ion binding]
Show all
320 aa
36.2 kDa
No 0
ZNF330-005
ENSP00000422599
ENST00000512809
D6RBR7 [Direct mapping]
Zinc finger protein 330
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0008270 [zinc ion binding]
Show all
229 aa
25.8 kDa
No 0
ZNF330-006
ENSP00000422966
ENST00000503649
D6R9C8 [Direct mapping]
Zinc finger protein 330
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0008270 [zinc ion binding]
Show all
140 aa
15.7 kDa
No 0
ZNF330-007
ENSP00000422251
ENST00000512738
D6R8Y9 [Direct mapping]
Zinc finger protein 330
Show all
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0005634 [nucleus]
GO:0005730 [nucleolus]
GO:0008270 [zinc ion binding]
Show all
153 aa
17.2 kDa
No 0

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