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RPL34

GENERAL INFORMATION

Gene name

 RPL34

Gene description

 Ribosomal protein L34

Protein class

 Predicted intracellular proteins
Ribosomal proteins

Predicted localization

 Intracellular

Number of transcripts

 5
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HUMAN PROTEIN ATLAS INFORMATION

RNA tissue category
HPA:Expressed in all
GTEx:Expressed in all
FANTOM5:Expressed in all

Protein evidence

 Evidence at protein level

Protein expression

 Cytoplasmic expression in several different tissue types.

DATA RELIABILITY

Data reliability
description

 Antibody staining mainly not consistent with RNA expression data.

Reliability score

 Uncertain based on 1 antibody.
HPA035139
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RNA AND PROTEIN EXPRESSION SUMMARY
RNA expression (TPM) Protein expression (score)
Brain
Caudate
N/A
Endocrine tissues
Bone marrow & immune system
Muscle tissues
Lung
Bronchus
N/A
Liver & gallbladder
Pancreas
Gastrointestinal tract
Kidney & urinary bladder
Male tissues
Female tissues
Vagina
N/A
Adipose & soft tissue
Skin
Cerebral cortex

Lymph node

Liver

Colon

Kidney

Testis

PROTEIN EXPRESSION OVERVIEW
Organ
Expression
Alphabetical

RNA EXPRESSION OVERVIEW
HPA dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
GTEx dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all
FANTOM5 dataset
Organ
Expression
Alphabetical
RNA tissue category: Expressed in all

GENE INFORMATION

Gene name

 RPL34 (HGNC Symbol)

Synonyms

 L34

Description

 Ribosomal protein L34 (HGNC Symbol)

Entrez gene summary

 Ribosomes, the organelles that catalyze protein synthesis, consist of a small 40S subunit and a large 60S subunit. Together these subunits are composed of 4 RNA species and approximately 80 structurally distinct proteins. This gene encodes a ribosomal protein that is a component of the 60S subunit. The protein belongs to the L34E family of ribosomal proteins. It is located in the cytoplasm. This gene originally was thought to be located at 17q21, but it has been mapped to 4q. Transcript variants derived from alternative splicing, alternative transcription initiation sites, and/or alternative polyadenylation exist; these variants encode the same protein. As is typical for genes encoding ribosomal proteins, there are multiple processed pseudogenes of this gene dispersed through the genome. [provided by RefSeq, Jul 2008]

Chromosome

 4

Cytoband

 q25

Chromosome location (bp)

 108620566 - 108630412

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000109475 (version 83.38)

Entrez gene

 6164

UniProt

 P49207 (UniProt - Evidence at protein level)

neXtProt

 NX_P49207

Antibodypedia

 RPL34 antibodies

PROTEIN BROWSER
RPL34-001
RPL34-002
RPL34-003
RPL34-005
RPL34-006

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
RPL34-001
ENSP00000378162
ENST00000394667
P49207 [Direct mapping]
60S ribosomal protein L34
A0A024RDH8 [Target identity:100%; Query identity:100%]
Ribosomal protein L34, isoform CRA_a
Show all
Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0042254 [ribosome biogenesis]
GO:0044267 [cellular protein metabolic process]
GO:0070062 [extracellular exosome]
Show all
 117 aa
13.3 kDa 		No 0
RPL34-002
ENSP00000378160
ENST00000394665
P49207 [Direct mapping]
60S ribosomal protein L34
A0A024RDH8 [Target identity:100%; Query identity:100%]
Ribosomal protein L34, isoform CRA_a
Show all
Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0042254 [ribosome biogenesis]
GO:0044267 [cellular protein metabolic process]
GO:0070062 [extracellular exosome]
Show all
 117 aa
13.3 kDa 		No 0
RPL34-003
ENSP00000378163
ENST00000394668
P49207 [Direct mapping]
60S ribosomal protein L34
A0A024RDH8 [Target identity:100%; Query identity:100%]
Ribosomal protein L34, isoform CRA_a
Show all
Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0042254 [ribosome biogenesis]
GO:0044267 [cellular protein metabolic process]
GO:0070062 [extracellular exosome]
Show all
 117 aa
13.3 kDa 		No 0
RPL34-005
ENSP00000423316
ENST00000506397
P49207 [Direct mapping]
60S ribosomal protein L34
A0A024RDH8 [Target identity:100%; Query identity:100%]
Ribosomal protein L34, isoform CRA_a
Show all
Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0042254 [ribosome biogenesis]
GO:0044267 [cellular protein metabolic process]
GO:0070062 [extracellular exosome]
Show all
 117 aa
13.3 kDa 		No 0
RPL34-006
ENSP00000423983
ENST00000502534
P49207 [Direct mapping]
60S ribosomal protein L34
A0A024RDH8 [Target identity:100%; Query identity:100%]
Ribosomal protein L34, isoform CRA_a
Show all
Ribosomal proteins
Predicted intracellular proteins
Protein evidence (Ezkurdia et al 2014)
Show all
GO:0000184 [nuclear-transcribed mRNA catabolic process, nonsense-mediated decay]
GO:0003723 [RNA binding]
GO:0003735 [structural constituent of ribosome]
GO:0005622 [intracellular]
GO:0005730 [nucleolus]
GO:0005737 [cytoplasm]
GO:0005829 [cytosol]
GO:0005840 [ribosome]
GO:0006412 [translation]
GO:0006413 [translational initiation]
GO:0006414 [translational elongation]
GO:0006415 [translational termination]
GO:0006614 [SRP-dependent cotranslational protein targeting to membrane]
GO:0010467 [gene expression]
GO:0016032 [viral process]
GO:0019058 [viral life cycle]
GO:0019083 [viral transcription]
GO:0022625 [cytosolic large ribosomal subunit]
GO:0042254 [ribosome biogenesis]
GO:0044267 [cellular protein metabolic process]
GO:0070062 [extracellular exosome]
Show all
 117 aa
13.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.