Expression of ANXA10 in cancer - Summary - The Human Protein Atlas

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ANXA10

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TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	ANXA10
Gene description	Annexin A10
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	2
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Group enriched (pancreatic cancer, stomach cancer, urothelial cancer)
HPA (cell line):	Group enriched (PC-3, RT4)
HPA (normal tissue):	Tissue enriched (stomach)

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Distinct nuclear expression in stomach and urinary bladder.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Supported based on 1 antibody. HPA005469
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (favourable).
Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Group enriched (pancreatic cancer, stomach cancer, urothelial cancer)

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA005469

GENE INFORMATION
Gene name	ANXA10 (HGNC Symbol)
Synonyms	ANX14
Description	Annexin A10 (HGNC Symbol)
Entrez gene summary	This gene encodes a member of the annexin family. Members of this calcium-dependent phospholipid-binding protein family play a role in the regulation of cellular growth and in signal transduction pathways. The function of this gene has not yet been determined. [provided by RefSeq, Jul 2008]
Chromosome	4
Cytoband	q32.3
Chromosome location (bp)	168092515 - 168187690
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000109511 (version 83.38)
Entrez gene	11199
UniProt	Q9UJ72 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UJ72
Antibodypedia	ANXA10 antibodies

PROTEIN BROWSER

ANXA10-001	ANXA10-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
ANXA10-001 ENSP00000352248 ENST00000359299	Q9UJ72 [Direct mapping] Annexin A10 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005515 [protein binding] GO:0005544 [calcium-dependent phospholipid binding] GO:0005739 [mitochondrion] Show all	324 aa 37.3 kDa	No	0
ANXA10-201 ENSP00000483710 ENST00000617524	A0A087X0X1 [Direct mapping] Annexin A10 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005509 [calcium ion binding] GO:0005544 [calcium-dependent phospholipid binding] Show all	323 aa 37.1 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.