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GRPEL1

GENERAL INFORMATION

Gene name

 GRPEL1

Gene description

 GrpE-like 1, mitochondrial (E. coli)

Protein class

 Predicted intracellular proteins

Predicted localization

 Intracellular

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Expressed in all
HPA (cell line):Expressed in all
HPA (normal tissue):Expressed in all

Protein evidence

 Evidence at protein level

Protein expression
normal tissue

 General cytoplasmic expression with a granular pattern.

ANTIBODY IHC RELIABILITY

Data reliability
description

 Antibody staining mainly consistent with RNA expression data. Presumed off target binding observed and disregarded.

Reliability score

 Supported based on 1 antibody.
HPA036647
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PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable).
Renal cancer p<0.001
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Expressed in all

PROTEIN EXPRESSION
Colorectal cancer
Breast cancer
Prostate cancer
Lung cancer
Liver cancer

STAINING SUMMARY
HPA036647

GENE INFORMATION

Gene name

 GRPEL1 (HGNC Symbol)

Synonyms

 FLJ25609, GrpE, hMGE

Description

 GrpE-like 1, mitochondrial (E. coli) (HGNC Symbol)

Entrez gene summary

Chromosome

 4

Cytoband

 p16.1

Chromosome location (bp)

 7058906 - 7068197

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000109519 (version 83.38)

Entrez gene

 80273

UniProt

 Q9HAV7 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9HAV7

Antibodypedia

 GRPEL1 antibodies

PROTEIN BROWSER
GRPEL1-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
GRPEL1-001
ENSP00000264954
ENST00000264954
Q9HAV7 [Direct mapping]
GrpE protein homolog 1, mitochondrial
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Predicted intracellular proteins
Protein evidence (Kim et al 2014)
Protein evidence (Ezkurdia et al 2014)
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GO:0000774 [adenyl-nucleotide exchange factor activity]
GO:0005739 [mitochondrion]
GO:0005759 [mitochondrial matrix]
GO:0006457 [protein folding]
GO:0006626 [protein targeting to mitochondrion]
GO:0042803 [protein homodimerization activity]
GO:0044267 [cellular protein metabolic process]
GO:0050790 [regulation of catalytic activity]
GO:0051082 [unfolded protein binding]
GO:0051087 [chaperone binding]
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 217 aa
24.3 kDa 		No 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.