Expression of NAA40 in cancer - Summary - The Human Protein Atlas

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NAA40

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	NAA40
Gene description	N(alpha)-acetyltransferase 40, NatD catalytic subunit
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	3
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HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Estimation of protein expression could not be performed. View primary data.

ANTIBODY IHC RELIABILITY
Data reliability description	RNA-based expert annotation gave inconclusive results. Antibody staining not consistent with RNA expression data.
Reliability score	Uncertain based on 1 antibody. HPA037816
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PROGNOSTIC SUMMARY
Prognostic marker in liver cancer (unfavourable).
Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA037816

GENE INFORMATION
Gene name	NAA40 (HGNC Symbol)
Synonyms	FLJ13848, NAT11
Description	N(alpha)-acetyltransferase 40, NatD catalytic subunit (HGNC Symbol)
Entrez gene summary
Chromosome	11
Cytoband	q13.1
Chromosome location (bp)	63938959 - 63957328
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000110583 (version 83.38)
Entrez gene	79829
UniProt	Q86UY6 (UniProt - Evidence at protein level)
neXtProt	NX_Q86UY6
Antibodypedia	NAA40 antibodies

PROTEIN BROWSER

NAA40-001	NAA40-004	NAA40-007

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NAA40-001 ENSP00000367024 ENST00000377793	Q86UY6 [Direct mapping] N-alpha-acetyltransferase 40 A0A024R5C6 [Target identity:100%; Query identity:100%] N-acetyltransferase 11, isoform CRA_a Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0006629 [lipid metabolic process] GO:0008080 [N-acetyltransferase activity] Show all	237 aa 27.2 kDa	No	0
NAA40-004 ENSP00000442055 ENST00000542163	Q86UY6 [Direct mapping] N-alpha-acetyltransferase 40 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0008080 [N-acetyltransferase activity] Show all	216 aa 24.8 kDa	No	0
NAA40-007 ENSP00000438639 ENST00000539656	F5H2C9 [Direct mapping] N-alpha-acetyltransferase 40 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		124 aa 13.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.