Expression of GPN3 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

GPN3

TISSUE

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	GPN3
Gene description	GPN-loop GTPase 3
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	7
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

Cytoplasmic expression at variable levels in several tissues.

ANTIBODY IHC RELIABILITY
Data reliability description	Pending external verification.
Reliability score	Uncertain based on 2 antibodies. HPA039764 , HPA047793
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (favourable) and liver cancer (unfavourable).
Renal cancer p<0.001 Liver cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA039764	HPA047793

GENE INFORMATION
Gene name	GPN3 (HGNC Symbol)
Synonyms	ATPBD1C, MGC14560
Description	GPN-loop GTPase 3 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q24.11
Chromosome location (bp)	110452484 - 110469268
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000111231 (version 83.38)
Entrez gene	51184
UniProt	Q9UHW5 (UniProt - Evidence at protein level)
neXtProt	NX_Q9UHW5
Antibodypedia	GPN3 antibodies

PROTEIN BROWSER

GPN3-001	GPN3-002	GPN3-003	GPN3-004	GPN3-007	GPN3-011	GPN3-201

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
GPN3-001 ENSP00000228827 ENST00000228827	Q9UHW5 [Direct mapping] GPN-loop GTPase 3 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0008152 [metabolic process] GO:0043234 [protein complex] Show all	284 aa 32.8 kDa	No	0
GPN3-002 ENSP00000443068 ENST00000537466	Q9UHW5 [Direct mapping] GPN-loop GTPase 3 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0008152 [metabolic process] GO:0043234 [protein complex] Show all	294 aa 33.9 kDa	No	0
GPN3-003 ENSP00000448159 ENST00000551079	H0YHZ5 [Direct mapping] GPN-loop GTPase 3 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0008152 [metabolic process] Show all	120 aa 13.8 kDa	No	0
GPN3-004 ENSP00000448335 ENST00000550228	H0YI19 [Direct mapping] GPN-loop GTPase 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0008152 [metabolic process] Show all	118 aa 13.9 kDa	No	0
GPN3-007 ENSP00000447480 ENST00000550974	F8W1F4 [Direct mapping] GPN-loop GTPase 3 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0008152 [metabolic process] Show all	159 aa 18.3 kDa	No	0
GPN3-011 ENSP00000474521 ENST00000549963	S4R3M7 [Direct mapping] GPN-loop GTPase 3 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		25 aa 2.6 kDa	No	0
GPN3-201 ENSP00000442770 ENST00000543199	Q9UHW5 [Direct mapping] GPN-loop GTPase 3 Show all	SPOCTOPUS predicted membrane proteins Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0003924 [GTPase activity] GO:0005515 [protein binding] GO:0005525 [GTP binding] GO:0008152 [metabolic process] GO:0043234 [protein complex] Show all	323 aa 37.4 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.