Expression of NAA25 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

NAA25

TISSUE

premium

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	NAA25
Gene description	N(alpha)-acetyltransferase 25, NatB auxiliary subunit
Protein class	Predicted intracellular proteins Predicted membrane proteins
Predicted localization	Intracellular,Membrane
Number of transcripts	2
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Expressed in all
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data.
Reliability score	Approved based on 1 antibody. HPA039322
	SHOW MORE

PROGNOSTIC SUMMARY
Prognostic marker in renal cancer (unfavourable), liver cancer (unfavourable) and endometrial cancer (unfavourable).
Renal cancer p<0.001 Liver cancer p<0.001 Endometrial cancer p<0.001 Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Expressed in all

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA039322

GENE INFORMATION
Gene name	NAA25 (HGNC Symbol)
Synonyms	C12orf30, FLJ13089
Description	N(alpha)-acetyltransferase 25, NatB auxiliary subunit (HGNC Symbol)
Entrez gene summary	This gene encodes the auxiliary subunit of the heteromeric N-terminal acetyltransferase B complex. This complex acetylates methionine residues that are followed by acidic or asparagine residues.[provided by RefSeq, Mar 2010]
Chromosome	12
Cytoband	q24.13
Chromosome location (bp)	112026689 - 112109022
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000111300 (version 83.38)
Entrez gene	80018
UniProt	Q14CX7 (UniProt - Evidence at protein level)
neXtProt	NX_Q14CX7
Antibodypedia	NAA25 antibodies

PROTEIN BROWSER

NAA25-001	NAA25-005

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
NAA25-001 ENSP00000261745 ENST00000261745	Q14CX7 [Direct mapping] N-alpha-acetyltransferase 25, NatB auxiliary subunit Show all	Predicted membrane proteins Prediction method-based Membrane proteins predicted by MDM MEMSAT3 predicted membrane proteins MEMSAT-SVM predicted membrane proteins Phobius predicted membrane proteins SCAMPI predicted membrane proteins SPOCTOPUS predicted membrane proteins THUMBUP predicted membrane proteins # TM segments-based 2TM proteins predicted by MDM Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0004596 [peptide alpha-N-acetyltransferase activity] GO:0005515 [protein binding] GO:0005654 [nucleoplasm] GO:0005737 [cytoplasm] GO:0005794 [Golgi apparatus] GO:0017196 [N-terminal peptidyl-methionine acetylation] GO:0031416 [NatB complex] Show all	972 aa 112.3 kDa	No	2
NAA25-005 ENSP00000447676 ENST00000547133	H0YHR9 [Direct mapping] N-alpha-acetyltransferase 25, NatB auxiliary subunit Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005515 [protein binding] Show all	141 aa 15.9 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.