Expression of OGFOD2 in cancer - Summary - The Human Protein Atlas

We use cookies to enhance the usability of our website. If you continue, we'll assume that you are happy to receive all cookies. More information. Don't show this again.

OGFOD2

TISSUE

premium

CELL

PATHOLOGY

PATHOLOGY ATLAS

GENE/PROTEIN

Antibody validation

Dictionary


Level of antibody staining/expression
	High Medium Low Not detected

GENERAL INFORMATION
Gene name	OGFOD2
Gene description	2-oxoglutarate and iron-dependent oxygenase domain containing 2
Protein class	Predicted intracellular proteins
Predicted localization	Intracellular
Number of transcripts	11
	SHOW MORE

HUMAN PROTEIN ATLAS INFORMATION

RNA category

TCGA (cancer tissue):	Mixed
HPA (cell line):	Expressed in all
HPA (normal tissue):	Expressed in all

Protein evidence

Evidence at protein level

Protein expression
normal tissue

General cytoplasmic expression.

ANTIBODY IHC RELIABILITY
Data reliability description	Antibody staining mainly consistent with RNA expression data. Pending external verification.
Reliability score	Approved based on 2 antibodies. HPA039448 , HPA040306
	SHOW MORE

PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all

RNA EXPRESSION OVERVIEW
TCGA dataset RNA cancer category: Mixed

PROTEIN EXPRESSION

Colorectal cancer

Prostate cancer

STAINING SUMMARY

HPA039448	HPA040306

GENE INFORMATION
Gene name	OGFOD2 (HGNC Symbol)
Synonyms	FLJ13491, FLJ37501
Description	2-oxoglutarate and iron-dependent oxygenase domain containing 2 (HGNC Symbol)
Entrez gene summary
Chromosome	12
Cytoband	q24.31
Chromosome location (bp)	122974580 - 122980043
Protein evidence	Evidence at protein level (all genes)
Ensembl	ENSG00000111325 (version 83.38)
Entrez gene	79676
UniProt	Q6N063 (UniProt - Evidence at transcript level)
neXtProt	NX_Q6N063
Antibodypedia	OGFOD2 antibodies

PROTEIN BROWSER

OGFOD2-001	OGFOD2-003	OGFOD2-004	OGFOD2-006	OGFOD2-007	OGFOD2-008	OGFOD2-009	OGFOD2-010	OGFOD2-011	OGFOD2-017	OGFOD2-020

PROTEIN INFORMATION
Splice variant	UniProt	Protein class	Gene ontology	Length & mass	Signal peptide (predicted)	Transmembrane regions (predicted)
OGFOD2-001 ENSP00000380544 ENST00000397389	Q6N063 [Direct mapping] 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Kim et al 2014) Protein evidence (Ezkurdia et al 2014) Show all	GO:0005506 [iron ion binding] GO:0016491 [oxidoreductase activity] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0031418 [L-ascorbic acid binding] GO:0051213 [dioxygenase activity] GO:0055114 [oxidation-reduction process] Show all	290 aa 32.1 kDa	No	0
OGFOD2-003 ENSP00000438192 ENST00000545317	Q6N063 [Direct mapping] 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 A0A024RBQ7 [Target identity:100%; Query identity:100%] 2-oxoglutarate and iron-dependent oxygenase domain containing 2, isoform CRA_b Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005506 [iron ion binding] GO:0016491 [oxidoreductase activity] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0031418 [L-ascorbic acid binding] GO:0051213 [dioxygenase activity] GO:0055114 [oxidation-reduction process] Show all	186 aa 20.3 kDa	No	0
OGFOD2-004 ENSP00000442476 ENST00000545056	F5H145 [Direct mapping] 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005506 [iron ion binding] GO:0016491 [oxidoreductase activity] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0031418 [L-ascorbic acid binding] GO:0055114 [oxidation-reduction process] Show all	160 aa 17.5 kDa	No	0
OGFOD2-006 ENSP00000228922 ENST00000228922	Q6N063 [Direct mapping] 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005506 [iron ion binding] GO:0016491 [oxidoreductase activity] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0031418 [L-ascorbic acid binding] GO:0051213 [dioxygenase activity] GO:0055114 [oxidation-reduction process] Show all	350 aa 39 kDa	No	0
OGFOD2-007 ENSP00000442817 ENST00000538755	Q6N063 [Direct mapping] 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 A0A024RBQ7 [Target identity:100%; Query identity:100%] 2-oxoglutarate and iron-dependent oxygenase domain containing 2, isoform CRA_b Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005506 [iron ion binding] GO:0016491 [oxidoreductase activity] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0031418 [L-ascorbic acid binding] GO:0051213 [dioxygenase activity] GO:0055114 [oxidation-reduction process] Show all	186 aa 20.3 kDa	No	0
OGFOD2-008 ENSP00000394175 ENST00000454694	Q6N063 [Direct mapping] 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 A0A024RBQ7 [Target identity:100%; Query identity:100%] 2-oxoglutarate and iron-dependent oxygenase domain containing 2, isoform CRA_b Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005506 [iron ion binding] GO:0016491 [oxidoreductase activity] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0031418 [L-ascorbic acid binding] GO:0051213 [dioxygenase activity] GO:0055114 [oxidation-reduction process] Show all	186 aa 20.3 kDa	No	0
OGFOD2-009 ENSP00000438327 ENST00000536150	Q6N063 [Direct mapping] 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 A0A024RBQ7 [Target identity:100%; Query identity:100%] 2-oxoglutarate and iron-dependent oxygenase domain containing 2, isoform CRA_b Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005506 [iron ion binding] GO:0016491 [oxidoreductase activity] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0031418 [L-ascorbic acid binding] GO:0051213 [dioxygenase activity] GO:0055114 [oxidation-reduction process] Show all	186 aa 20.3 kDa	No	0
OGFOD2-010 ENSP00000444436 ENST00000545612	Q6N063 [Direct mapping] 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 A0A024RBQ7 [Target identity:100%; Query identity:100%] 2-oxoglutarate and iron-dependent oxygenase domain containing 2, isoform CRA_b Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005506 [iron ion binding] GO:0016491 [oxidoreductase activity] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0031418 [L-ascorbic acid binding] GO:0051213 [dioxygenase activity] GO:0055114 [oxidation-reduction process] Show all	186 aa 20.3 kDa	No	0
OGFOD2-011 ENSP00000444608 ENST00000538628	Q6N063 [Direct mapping] 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 A0A024RBQ7 [Target identity:100%; Query identity:100%] 2-oxoglutarate and iron-dependent oxygenase domain containing 2, isoform CRA_b Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005506 [iron ion binding] GO:0016491 [oxidoreductase activity] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0031418 [L-ascorbic acid binding] GO:0051213 [dioxygenase activity] GO:0055114 [oxidation-reduction process] Show all	186 aa 20.3 kDa	No	0
OGFOD2-017 ENSP00000442083 ENST00000537966	F5H890 [Direct mapping] 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all		207 aa 22.6 kDa	No	0
OGFOD2-020 ENSP00000438003 ENST00000536439	F5H145 [Direct mapping] 2-oxoglutarate and iron-dependent oxygenase domain-containing protein 2 Show all	Predicted intracellular proteins Protein evidence (Ezkurdia et al 2014) Show all	GO:0005506 [iron ion binding] GO:0016491 [oxidoreductase activity] GO:0016705 [oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen] GO:0031418 [L-ascorbic acid binding] GO:0055114 [oxidation-reduction process] Show all	160 aa 17.5 kDa	No	0

Contact

contact@proteinatlas.org

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.