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Membranous staining of various intensities was observed in carcinoid. Neuropil in gliomas showed strong cytoplasmic staining. All other cancers were negative.
GENE INFORMATION
Gene name
STX2 (HGNC Symbol)
Synonyms
EPIM, EPM, STX2A, STX2B, STX2C
Description
Syntaxin 2 (HGNC Symbol)
Entrez gene summary
The product of this gene belongs to the syntaxin/epimorphin family of proteins. The syntaxins are a large protein family implicated in the targeting and fusion of intracellular transport vesicles. The product of this gene regulates epithelial-mesenchymal interactions and epithelial cell morphogenesis and activation. Alternatively spliced transcript variants encoding different isoforms have been identified. [provided by RefSeq, Jul 2008]