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IL26

GENERAL INFORMATION

Gene name

 IL26

Gene description

 Interleukin 26

Protein class

 Plasma proteins
Predicted secreted proteins

Predicted localization

 Secreted

Number of transcripts

 1
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HUMAN PROTEIN ATLAS INFORMATION

RNA category
TCGA (cancer tissue):Not detected
HPA (cell line):Cell line enriched (HDLM-2)
HPA (normal tissue):Tissue enhanced (appendix, tonsil, urinary bladder)

Protein evidence

 Evidence at protein level

ANTIBODY IHC RELIABILITY

Reliability score

 Pending cancer tissue analysis.

PROGNOSTIC SUMMARY
Gene product is not prognostic.
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RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Not detected

PROTEIN EXPRESSION

Pending cancer tissue analysis

STAINING SUMMARY

 

GENE INFORMATION

Gene name

 IL26 (HGNC Symbol)

Synonyms

 AK155, IL-26

Description

 Interleukin 26 (HGNC Symbol)

Entrez gene summary

 This gene was identified by its overexpression specifically in herpesvirus samimiri-transformed T cells. The encoded protein is a member of the IL10 family of cytokines. It is a secreted protein and may function as a homodimer. This protein is thought to contribute to the transformed phenotype of T cells after infection by herpesvirus samimiri. [provided by RefSeq, Jul 2008]

Chromosome

 12

Cytoband

 q15

Chromosome location (bp)

 68201351 - 68225821

Protein evidence

 Evidence at protein level (all genes)

Ensembl

 ENSG00000111536 (version 83.38)

Entrez gene

 55801

UniProt

 Q9NPH9 (UniProt - Evidence at protein level)

neXtProt

 NX_Q9NPH9

Antibodypedia

 IL26 antibodies

PROTEIN BROWSER
IL26-001

PROTEIN INFORMATION

Splice variant

UniProt

Protein class

Gene ontology

Length & mass

Signal peptide
(predicted)

Transmembrane regions
(predicted)
IL26-001
ENSP00000229134
ENST00000229134
Q9NPH9 [Direct mapping]
Interleukin-26
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Predicted secreted proteins
   Secreted proteins predicted by MDSEC
   SignalP predicted secreted proteins
   Phobius predicted secreted proteins
   SPOCTOPUS predicted secreted proteins
Plasma proteins
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GO:0005125 [cytokine activity]
GO:0005615 [extracellular space]
GO:0005829 [cytosol]
GO:0006954 [inflammatory response]
GO:0006955 [immune response]
GO:0007267 [cell-cell signaling]
GO:0032874 [positive regulation of stress-activated MAPK cascade]
GO:0045944 [positive regulation of transcription from RNA polymerase II promoter]
GO:0046427 [positive regulation of JAK-STAT cascade]
GO:0050680 [negative regulation of epithelial cell proliferation]
GO:0050715 [positive regulation of cytokine secretion]
GO:0051897 [positive regulation of protein kinase B signaling]
GO:0070374 [positive regulation of ERK1 and ERK2 cascade]
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 171 aa
19.8 kDa 		Yes 0

Contact

The Project

The Human Protein Atlas

The Human Protein Atlas project is funded
by the Knut & Alice Wallenberg foundation.