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Group enriched (colorectal cancer, pancreatic cancer, stomach cancer)
HPA (cell line):
Cell line enriched (CAPAN-2)
HPA (normal tissue):
Group enriched (duodenum, small intestine)
Protein evidence
Evidence at protein level
ANTIBODY IHC RELIABILITY
Reliability score
Pending cancer tissue analysis.
PROGNOSTIC SUMMARY
Gene product is not prognostic.
Show all
RNA EXPRESSION OVERVIEW
TCGA dataset
RNA cancer category: Group enriched (colorectal cancer, pancreatic cancer, stomach cancer)
PROTEIN EXPRESSION
Pending cancer tissue analysis
STAINING SUMMARY
GENE INFORMATION
Gene name
APOBEC1 (HGNC Symbol)
Synonyms
APOBEC-1, BEDP, CDAR1, HEPR
Description
Apolipoprotein B mRNA editing enzyme, catalytic polypeptide 1 (HGNC Symbol)
Entrez gene summary
This gene encodes a member of the cytidine deaminase enzyme family. The encoded protein forms a multiple-protein editing holoenzyme with APOBEC1 complementation factor (ACF) and APOBEC1 stimulating protein (ASP). This holoenzyme is involved in the editing of C-to-U nucleotide bases in apolipoprotein B and neurofibromatosis-1 mRNAs. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Feb 2015]